Protein Alignment CG9265 and RDH16

DIOPT Version :10

• Sequence 1: NP_610081.3
• Gene: CG9265 / 35369
• FlyBaseID: FBgn0032910
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_003699.3
• Gene: RDH16 / 8608
• HGNCID: 29674
• Length: 317
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 62/225 - (27%)
• Similarity: 106/225 - (47%)
• Gaps: 27/225 - (12%)

  Fly    59 WFIICCIGYILQDLYYIAFGYPEKE----LNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDIN 119
            |..:.    :...|||:...|.|::    |......|||..:|.|:|||.:|...|.:|:...:.
Human     2 WLYLA----VFVGLYYLLHWYRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAACLT 62

  Fly   120 KKGIAETVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITL--LINNAGVVSGLHLLDT 182
            :|| ||  |:..:.....:...:|::|.|.|..||..:::.|.|..|  |:||||:    .|...
Human    63 EKG-AE--QLRGQTSDRLETVTLDVTKTESVAAAAQWVKECVRDKGLWGLVNNAGI----SLPTA 120

  Fly   183 PDHLIERS-----FNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAA 242
            |:.|:.:.     .:||::.....|.:.|| ::...||.:..::|:.|.|.:.. ..||.||:..
Human   121 PNELLTKQDFVTILDVNLLGVIDVTLSLLP-LVRRARGRVVNVSSVMGRVSLFG-GGYCISKYGV 183

  Fly   243 VGFDEALRLELEVLGHTNIRTTCICPFFIQ 272
            ..|.::||.||...|   ::...|.|.:.:
Human   184 EAFSDSLRRELSYFG---VKVAMIEPGYFK 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_610081.3	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	55/192 (29%)
RDH16	NP_003699.3	Rossmann-fold NAD(P)(+)-binding proteins	30..305	CDD:473865	55/193 (28%)