Protein Alignment CG9265 and SRL4

DIOPT Version :10

• Sequence 1: NP_610081.3
• Gene: CG9265 / 35369
• FlyBaseID: FBgn0032910
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_015292.1
• Gene: SRL4 / 856074
• SGDID: S000005954
• Length: 281
• Species: Saccharomyces cerevisiae
• Alignment Length: 286
• Identity: 68/286 - (23%)
• Similarity: 110/286 - (38%)
• Gaps: 57/286 - (19%)

  Fly    68 ILQDLY-YIAFGYPEKELNTDIALITGGGNGLGRLLAER-LGKMGTKVV----IWDINKKGIAET 126
            :|...| |:..|......:..:.:|.|..|.||..|.|. :....|||:    |..||.|....:
Yeast     8 VLVSFYQYVGLGKKFHPSHDTVLIIGGSSNELGIELCETFIEDYHTKVINIDTIDSINGKNARRS 72

  Fly   127 VQIVEEAGGYCKGYVVDISKKEE--VY-KAADVIRDEVGDITLLINN--AGVVSGLHLLDTPDHL 186
            .::.....  ||.: .||...||  :| :..::|.      |:||||  .|:.|.|...|....|
Yeast    73 EKLYTFIS--CKDF-SDIKCLEESMLYLQNLEIIP------TVLINNMQEGIESTLLKEDKFLRL 128

  Fly   187 IERSFN-------VNVMAHFWTTKAFL----PKM----IENDRG-HIATIASLAGHVGISKLVDY 235
            .|.|.|       .|:.:....||..|    ||:    .|..:| :|..|:|:...........:
Yeast   129 DEESLNEFEKIVRYNLQSVILITKFCLSNIFPKVQAEAQEKAKGFYIVNISSVLTLKPCKSGTHF 193

  Fly   236 CASKFAAVGFDEALRLELEVL-GHTNIRT-TCICPFFIQATGMFDDVNARW---VPTLNPNDV-- 293
            ..||.....|.:.:..||::. .:.|::| ....|.|        :..|.|   .|:::.:.|
Yeast   194 ITSKCGINSFHDGITSELKLKDSNLNVKTLIAYLPSF--------ESEAHWKRLSPSISKHLVHC 250

  Fly   294 ------ADRVIAAIRKNEKLAVIPGF 313
                  .|.::.:.|....:.:|.||
Yeast   251 LLEGRYGDTILESKRSIGDILLITGF 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_610081.3	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	64/265 (24%)
SRL4	NP_015292.1	Rossmann-fold NAD(P)(+)-binding proteins	28..>230	CDD:473865	54/210 (26%)