Protein Alignment CG9265 and HSD17B11

DIOPT Version :10

• Sequence 1: NP_610081.3
• Gene: CG9265 / 35369
• FlyBaseID: FBgn0032910
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Alignment Length: 279
• Identity: 114/279 - (40%)
• Similarity: 167/279 - (59%)
• Gaps: 18/279 - (6%)

  Fly    61 IICCIGYILQDLYYIAFGYPEKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAE 125
            |:|.    |:....:......|.:..:|.||||.|:|:|||.|....|:.:|:|:|||||.|:.|
Human    15 IVCS----LESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEE 75

  Fly   126 TVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERS 190
            |....:..|.....:|||.|.:|::|.:|..::.|:||:::|:||||||....|..|.|..||::
Human    76 TAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKT 140

  Fly   191 FNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEV 255
            |.|||:|||||||||||.|.:|:.|||.|:||.||||.:..|:.||:||||||||.:.|..||..
Human   141 FEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAA 205

  Fly   256 LGHTNIRTTCICPFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSF 320
            |..|.::|||:||.|:. ||...:.:....|||.|.:|.:|::..|...:|:..||..:..|.:
Human   206 LQITGVKTTCLCPNFVN-TGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTT- 268

  Fly   321 KWTFPWGCVGGLLKRLVPD 339
                        |:|::|:
Human   269 ------------LERILPE 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_610081.3	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	107/239 (45%)
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	110/252 (44%)