Protein Alignment CG9265 and HSD17B13

DIOPT Version :10

• Sequence 1: NP_610081.3
• Gene: CG9265 / 35369
• FlyBaseID: FBgn0032910
• Length: 399
• Species: Drosophila melanogaster
• Sequence 2: NP_835236.2
• Gene: HSD17B13 / 345275
• HGNCID: 18685
• Length: 300
• Species: Homo sapiens
• Alignment Length: 272
• Identity: 109/272 - (40%)
• Similarity: 163/272 - (59%)
• Gaps: 5/272 - (1%)

  Fly    56 DVAWFIICCIGYILQDLYYIAFGYPE--KELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDI 118
            ::...:|..|...|:.|  :.|..|:  |.:..:|.||||.|:|:||.......|..:.:|:|||
Human     6 EILLLLITIIYSYLESL--VKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDI 68

  Fly   119 NKKGIAETVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTP 183
            ||:|:.||.....:.|.....||||.|.:||:|::.:.::.||||:|:::||||.|....||.|.
Human    69 NKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTK 133

  Fly   184 DHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEA 248
            |..|.::|.||::.|||.|||.||.|:|.:.|||.|:||:.||.||..|:.||:||||||||...
Human   134 DEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRG 198

  Fly   249 LRLELEVLGHTNIRTTCICPFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGF 313
            |..||:.||.|.|:|:|:||.|:. ||...:.:.|..|.|..::|...:|..|..|:|:..:|.:
Human   199 LTSELQALGKTGIKTSCLCPVFVN-TGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSY 262

  Fly   314 LKVLLSFKWTFP 325
            :.:.|..:...|
Human   263 INIFLRLQKFLP 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_610081.3	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	102/238 (43%)
HSD17B13	NP_835236.2	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	102/238 (43%)