DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9265 and Hsd17b13

DIOPT Version :9

Sequence 1:	NP_001260655.1	Gene:	CG9265 / 35369	FlyBaseID:	FBgn0032910	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_932147.2	Gene:	Hsd17b13 / 243168	MGIID:	2140804	Length:	304	Species:	Mus musculus

Alignment Length:	246	Identity:	101/246 - (41%)
Similarity:	148/246 - (60%)	Gaps:	3/246 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 IAFGYP--EKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAGGYC 137
            :.|..|  .|.:.....||||.|:|:|||.|....|..:::|:|||||:|:.||.....:.|...
Mouse    23 VKFFIPRRRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLGAVV 87

  Fly   138 KGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTT 202
            ..:|||.|.:.|:|.:.|.::.||||:.:::||||.:....||...|..|.::|.||::.|||..
Mouse    88 HVFVVDCSNRAEIYNSVDQVKREVGDVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWII 152

  Fly   203 KAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGHTNIRTTCIC 267
            ||.||.|:..:.|||.|:||:.||..|..|:.||:||||||||..||..||:.||.|.|:|:|:|
Mouse   153 KALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLC 217

  Fly   268 PFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLL 318
            |.|:. ||...:.:.|..|.|.|.:||..:|..|..|:|:..:|.::.:.|
Mouse   218 PVFVN-TGFTKNPSTRLWPVLEPEEVARSLINGILTNKKMIFVPSYINISL 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_001260655.1	fabG	82..299	CDD:235546	93/216 (43%)
CG9265	NP_001260655.1	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	98/231 (42%)
Hsd17b13	NP_932147.2	adh_short	37..228	CDD:278532	86/191 (45%)
		17beta-HSDXI-like_SDR_c	38..269	CDD:187598	98/231 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	276..304
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2768
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	231	1.000	Inparanoid score	I3425
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.970