DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9265 and SDR16C5

DIOPT Version :9

Sequence 1:	NP_001260655.1	Gene:	CG9265 / 35369	FlyBaseID:	FBgn0032910	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_001304978.1	Gene:	SDR16C5 / 195814	HGNCID:	30311	Length:	318	Species:	Homo sapiens

Alignment Length:	258	Identity:	115/258 - (44%)
Similarity:	164/258 - (63%)	Gaps:	5/258 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 ILQDLYYIAFGYPEKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEE 132
            :|:.:.:.....|.|.:..:|.||||.|:|||||||.:..::|:.:|:|||||:|..||.::..|
Human    22 LLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMARE 86

  Fly   133 AGG-YCKGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVM 196
            ||. ....|..|.|:||.||:.||.::.||||:::||||||:|:|...||.||.|:|:||:||..
Human    87 AGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFK 151

  Fly   197 AHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGHTNI 261
            ||.||.|||||.||.||.||:..|:|.||..|::.|.|||||||||.||.|::.:|..|.....|
Human   152 AHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216

  Fly   262 RTTCICPFFIQATGMFDDVNA---RWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFK 321
            :||.:|||||: ||||:....   ..:|.|.|....::::.||.:.:....:|..|..::..|
Human   217 KTTIVCPFFIK-TGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLK 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_001260655.1	fabG	82..299	CDD:235546	108/220 (49%)
CG9265	NP_001260655.1	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	112/238 (47%)
SDR16C5	NP_001304978.1	adh_short	41..231	CDD:278532	102/190 (54%)
SDR16C5	NP_001304978.1	17beta-HSDXI-like_SDR_c	42..280	CDD:187598	112/238 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I2872
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15039
Inparanoid	1	1.050	223	1.000	Inparanoid score	I3528
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	1	1.000	-	-		otm41147
orthoMCL	1	0.900	-	-		OOG6_100599
Panther	1	1.100	-	-	LDO	PTHR24322
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1734
SonicParanoid	1	1.000	-	-		X140
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.900