DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9265 and dhs-29

DIOPT Version :9

Sequence 1:	NP_001260655.1	Gene:	CG9265 / 35369	FlyBaseID:	FBgn0032910	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_509294.1	Gene:	dhs-29 / 181027	WormBaseID:	WBGene00000992	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	282	Identity:	89/282 - (31%)
Similarity:	146/282 - (51%)	Gaps:	18/282 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LWNTWDAFADVAWFIICCIGYILQDLY-------YIAFGYPEKELNTDIALITGGGNGLGRLLAE 104
            ::.:|      ||.:...:|..|:.|:       :......:|.:.....:|||||:||||.:|.
Worm     1 MYTSW------AWKLWSTLGVALRILFIDIPMDIHRFLNLRQKSVQGQTVIITGGGSGLGRAMAL 59

  Fly   105 RLGKMGTKVVIWDINKKGIAETVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITLLIN 169
            ...|...||.|.|:||:|..|||:.:...|...|.:..|||..:.:.|.|..|.|..||:.::|.
Worm    60 DFAKRKAKVAIIDVNKEGGLETVKTIAAEGNMAKFWYCDISDVDNMKKTAKEIEDTFGDVNIVIC 124

  Fly   170 NAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVD 234
            ||.::|....::..|.|:.:..:||:.....|.:||||||...:.|||..:.|:||..|.:..:.
Worm   125 NAAILSFTSFMEISDELLRKCLDVNIFGTINTIRAFLPKMETKNDGHIVCVCSIAGWSGETMGLS 189

  Fly   235 YCASKFAAVGFDEALRLELEVLGHTNIRTTCICPFFIQATGMFDDVNAR----WVPTLNPNDVAD 295
            ||.||||..|..|:|::||...|...|:||.:.|:|.: |.|..:.|.|    |.|.::....:.
Worm   190 YCTSKFAVRGAMESLQMELRDRGLEGIKTTTLYPYFAR-TPMILENNMRPTCTWFPFMSIRSCSK 253

  Fly   296 RVIAAIRKNEKLAVIPGFLKVL 317
            |::.:|.|.:..|.:|.::.::
Worm   254 RMVDSILKEKVHAFVPSYITLI 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9265	NP_001260655.1	fabG	82..299	CDD:235546	79/220 (36%)
CG9265	NP_001260655.1	17beta-HSDXI-like_SDR_c	88..328	CDD:187598	82/234 (35%)
dhs-29	NP_509294.1	adh_short	42..230	CDD:278532	72/188 (38%)
		NADB_Rossmann	43..281	CDD:304358	82/234 (35%)
		DUF4499	322..416	CDD:291595
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1373099at2759
OrthoFinder	1	1.000	-	-		FOG0000227
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100599
Panther	1	1.100	-	-	O	PTHR24322
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820