Protein Alignment Itgbn and ITGBL1

DIOPT Version :9

• Sequence 1: NP_001303333.1
• Gene: Itgbn / 35368
• FlyBaseID: FBgn0010395
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_004782.1
• Gene: ITGBL1 / 9358
• HGNCID: 6164
• Length: 494
• Species: Homo sapiens
• Alignment Length: 391
• Identity: 112/391 - (28%)
• Similarity: 152/391 - (38%)
• Gaps: 107/391 - (27%)

  Fly   458 CPCQ----ETPDPENEEGRFLCDYKGYLYCGMCECDEGWTGTYCNCPT--DATNVTSNEALLQKC 516
            |.|.    ||.|.....|...||      ||.|:||:||.|..|..||  |.|...||    |.|
Human    89 CECHEWVCETYDGSTCAGHGKCD------CGKCKCDQGWYGDACQYPTNCDLTKKKSN----QMC 143

  Fly   517 RQPFSDKSTSELVCSNHGDCDCGTCLCDPG-----YTGPFCEC--RECLDCD-EKL----ADCFC 569
                  |::.:::|||.|.|.||.|.||..     ..|.||||  |||:|.: |::    ..|:|
Human   144 ------KNSQDIICSNAGTCHCGRCKCDNSDGSGLVYGKFCECDDRECIDDETEEICGGHGKCYC 202

  Fly   570 GQCVCKYGWSGSKC--NCD----GDTDACVGPTGEICSERGTCQCEECQCEE--------PYLGK 620
            |.|.||.||.|.||  .||    .....|..|.|:|||.||||.|.||.|.:        ...|.
Human   203 GNCYCKAGWHGDKCEFQCDITPWESKRRCTSPDGKICSNRGTCVCGECTCHDVDPTGDWGDIHGD 267

  Fly   621 FCEIDPEKD---------NKLCLFYEPC-------------------VTCLIEQKQGMGVCENLT 657
            .||.| |:|         :..|..:..|                   .:|.:..::.:..|:..:
Human   268 TCECD-ERDCRAVYDRYSDDFCSGHGQCNCGRCDCKAGWYGKKCEHPQSCTLSAEESIRKCQGSS 331

  Fly   658 EI-CSSLDRQE-----TYP------YNFVHELDPEQDQCLVRLV-NKHG------IQCDSFFVYQ 703
            :: ||...:.|     .||      |....|.|..:.:.|..:| ..||      ..|:..:..:
Human   332 DLPCSGRGKCECGKCTCYPPGDRRVYGKTCECDDRRCEDLDGVVCGGHGTCSCGRCVCERGWFGK 396

  Fly   704 VIDH---SNFLTIQAVD-CEPPDYVALVGYISAFTLLIGLLIIFIILWYIRAK----DAREYAKF 760
            :..|   .|....|:.: ||..|.:...|..|..   .|..|.....|||..:    |.|:..|.
Human   397 LCQHPRKCNMTEEQSKNLCESADGILCSGKGSCH---CGKCICSAEEWYISGEFCDCDDRDCDKH 458

  Fly   761 E 761
            :
Human   459 D 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Itgbn	NP_001303333.1	INB	38..460	CDD:197563	1/1 (100%)
		EGF_2	524..552	CDD:285248	11/32 (34%)
		Integrin_b_cyt	748..785	CDD:285884	5/18 (28%)
ITGBL1	NP_004782.1	Cysteine-rich tandem repeats	51..494		112/391 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1226
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910