Protein Alignment Itgbn and itgb1b.2

DIOPT Version :9

• Sequence 1: NP_001303333.1
• Gene: Itgbn / 35368
• FlyBaseID: FBgn0010395
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_998093.2
• Gene: itgb1b.2 / 405864
• ZFINID: ZDB-GENE-040426-2598
• Length: 613
• Species: Danio rerio
• Alignment Length: 648
• Identity: 204/648 - (31%)
• Similarity: 330/648 - (50%)
• Gaps: 78/648 - (12%)

  Fly    12 IYLVFLIAEISHSDADSIDDQC--RHADSCERCLSAHLECAWCTDKEYQVGYRCLSRRQLLNYNC 74
            :.|..|:..:|:..|::..:.|  .:|.:|..|:....:|.||.|.:::.. ||.....:....|
Zfish     6 LLLSALLGFVSYVGANTDSNPCISANAKTCGECIQIGPQCVWCKDPDFKPS-RCDDIESMAKAGC 69

  Fly    75 SETDIYENQPVLDVLQDKPLKDYETS-------DQAVQVTPQRAYLKLVKGNTQRMKLSYRTARN 132
            :...:...:..:.:.::||:.:.:|.       |:..|:.||:..|.|..|..|:..|.::.|.:
Zfish    70 TADGVENPRGAVTIDKNKPVTNRKTDGGQNLRPDEITQIQPQKVKLNLRSGEAQKFTLKFKRAED 134

  Fly   133 NPLDLYVLMDLTWTMRDDKKTLEELGAQLSQTLKNLTGNYRLGFGSFADKPTLPMILPQHRENPC 197
            .|:|||.||||:.:|..:.:..:.||.:|:..:|::|.:.|:|||||..||::       :.|||
Zfish   135 YPIDLYFLMDLSHSMLSNLENFKNLGTELANEMKDITKDLRIGFGSFFRKPSI-------QTNPC 192

  Fly   198 AAERATCEPTYGYRHQLSLTDDIPAFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQA 262
            ..:  .|...:.|.:.||||||...||..::..|.:||||:.|.||:||||..|||..|||:...
Zfish   193 FPD--NCIAPFSYFNVLSLTDDHALFTQEISKLKTSGNLDSSEAGLEALMQAAVCTDVIGWRNVT 255

  Fly   263 RKVVILVTDGFMHLAGDGLLAGIIQRNDKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVI 327
            | :::..||..:..:|||...||::.||.:|.|:. ..||.|...|||||.::...:....|:.|
Zfish   256 R-LLVFFTDAGLRFSGDGKRGGIVRLNDGKCLLDD-NMYTRSDYSDYPSLSQLVDTVTDNSIHTI 318

  Fly   328 FAVTEEVVSSYWELSALMKEISYVDILSADSSNILELIKKSYESLIKRTQ--FADNS--PDFIDM 388
            |||||:....|.||||.:.. |.|..||....|:.:|:   .::||..:.  ..:||  ||.:.:
Zfish   319 FAVTEQYRDLYQELSAKVPN-SAVGTLSTSGDNLAKLV---IDALIPLSSEVIVENSKLPDGVSI 379

  Fly   389 AYYTDC----GGQFPSLQKRNYCNNVTLGKQIDFYVDVTLKKYPDNQVYTHKIRVEETSLSEFMD 449
            :|.:.|    .|:....:|   |:|:::|.::.|.:::|.|..| ::.....|:::....||  :
Zfish   380 SYVSHCKNGVNGRGEDGRK---CSNISIGDEVLFDIEITAKGCP-SKGKPETIKIKPLGFSE--E 438

  Fly   450 LDVELQRPCPCQETPD-----PENEEGRFLCDYKGYLYCGMCECDEGWTGTYCNCPTDATNVTSN 509
            :::.|...|.|:...|     ||...|      :|.|.||:|.|:||.:|..|.|..|
Zfish   439 VEIFLNYICECECHKDGIKNSPECSGG------QGTLECGVCRCNEGRSGRICECTQD------- 490

  Fly   510 EALLQKCRQPFSDKSTSELVCSNHGDCDCGTCLC------DPGYTGPFCECRECLDCD---EKLA 565
              |...|:...|..     :|||:|:|.||||.|      :..|:|.:|||.. ..||   .||.
Zfish   491 --LDAYCQMDMSSG-----ICSNNGECVCGTCECKKRENPEERYSGRYCECNN-FSCDRFNNKLC 547

  Fly   566 D----CFCGQCVCKYGWSGSKCNCDGDTDACVGPTGEICSERGTCQCEECQCEEPYLGKFCEI 624
            .    |.||||.|::.::||.|.|..||.:|:.....||:..|.|:|.:|:|.:...|..|||
Zfish   548 GGHGRCMCGQCACEFNYAGSACQCSMDTSSCLASNKLICNGHGICECGQCKCLDNCQGPTCEI 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Itgbn	NP_001303333.1	INB	38..460	CDD:197563	135/436 (31%)
		EGF_2	524..552	CDD:285248	12/33 (36%)
		Integrin_b_cyt	748..785	CDD:285884
itgb1b.2	NP_998093.2	Integrin_beta	34..449	CDD:278776	135/436 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1226
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223415at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100678
Panther	1	1.100	-	-	O	PTHR10082
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.780