Protein Alignment Itgbn and C05D9.3

DIOPT Version :10

• Sequence 1: NP_523608.2
• Gene: Itgbn / 35368
• FlyBaseID: FBgn0010395
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001360655.1
• Gene: C05D9.3 / 182254
• WormBaseID: WBGene00015472
• Length: 453
• Species: Caenorhabditis elegans
• Alignment Length: 651
• Identity: 129/651 - (19%)
• Similarity: 191/651 - (29%)
• Gaps: 293/651 - (45%)

  Fly    12 IYLVFLIAEISHSDADSIDDQCRHAD---SCERCLSAHLECAWCTDKEYQVGYRCLSRRQLLNYN 73
            |:.:.|:..::..  :|.|..|...|   ||.:|:.||.|||||.|....:..||..:.:..|..
 Worm     5 IFFITLLTIVAAQ--ESADQLCSSFDAQQSCGQCIKAHAECAWCIDPHSSLTNRCQLKSKFTNET 67

  Fly    74 CSETDIYENQPVLDVLQDKPLKDYETSDQAVQVTPQRAYLKLVKGNTQRMKLSYRTARNNPLDLY 138
            |:...:|                          :||.|.:|:              .:|.||:
 Worm    68 CTPHLVY--------------------------SPQTAQVKI--------------QQNLPLE-- 90

  Fly   139 VLMDLTWTMRDDKKTLEELGAQLSQTLKNLTGNYRLGFGSFADKPTLPMILPQHRENPCAAERAT 203
                   |.:.|.||:.....|....                      .::|.|          :
 Worm    91 -------TKQHDGKTIVRQQPQAVSV----------------------RLMPSH----------S 116

  Fly   204 CEPTYGYRHQLSLTDDIPAFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQARKVVIL 268
            ...::.|.||
 Worm   117 ATVSFKYLHQ------------------------------------------------------- 126

  Fly   269 VTDGFMHLAGDGLLAGIIQRNDKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEE 333
             ||                                      ||
 Worm   127 -TD--------------------------------------PS---------------------- 130

  Fly   334 VVSSYWELSALMKEISYVDILSADSSNILELIKKSYESLIKRTQFADNSPDFIDMAYYTDCGGQF 398
                                            ::|.|......|.:|.....:.:.::..|.|:
 Worm   131 --------------------------------RRSTEPETMEIQTSDVKDTPLQLKFFIVCDGE- 162

  Fly   399 PSLQKRNYCNNVTLGKQIDFYVDVTLKKYPDNQVYTHKIRVEETSLSEFMDLDVEL----QRP-- 457
              |::...|                  :..:||:...||.|...|.|...|:.:.:    ||.
 Worm   163 --LKETKSC------------------RVQNNQIVEFKIEVLVNSCSSTGDITLSVGILRQRTIA 207

  Fly   458 ---------CPCQETPDPENEEGRFLCDYKGYLYCGMCECDEGWTGTYCNCPTDATNVTSNEALL 513
                     |.|::.|:..:.    ||...|:|.||.|.||:...|..|.||..:..|:....|.
 Worm   208 GLYVTTICGCECEKHPEINSR----LCHQNGHLVCGQCVCDQSRGGDKCECPLASHGVSKASELE 268

  Fly   514 QKCRQPFSDKSTSELVCSNHGDCDCGTCLCD-PGYTGPFCEC--REC-LDCDEKLAD----CFCG 570
            .|||  |:..|.   |||..|.|.||.|.|: |..||.||:|  ..| |..:.|:..    |.||
 Worm   269 DKCR--FNSSSP---VCSASGKCKCGQCQCNKPTVTGKFCQCDNDSCPLAVNGKVCSGNGVCDCG 328

  Fly   571 QCVCKYGWSGSKCNCDGDTDACVGPTGEICSERGTCQCEECQCEEPYLGKFCEID-----PEKDN 630
            .|.|:.||....|:|...::.|| ..||:||..|.|:|..|.|.....|.||..|     ||:.:
 Worm   329 VCKCEMGWERDDCSCSTASNNCV-DNGELCSNNGRCECNRCVCNMGKTGAFCGSDEKTPAPEEKD 392

  Fly   631 K 631
            |
 Worm   393 K 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Itgbn	NP_523608.2	INB	38..460	CDD:197563	56/436 (13%)
		EGF_2	529..552	CDD:400365	12/23 (52%)
		Integrin_b_cyt	752..785	CDD:462580
C05D9.3	NP_001360655.1	vWFA	32..>123	CDD:469594	30/171 (18%)
		I-EGF_1	219..247	CDD:465729	11/31 (35%)
		gliding_CglD	<239..370	CDD:468178	52/136 (38%)