Protein Alignment Itgbn and Itgb2l

DIOPT Version :10

• Sequence 1: NP_523608.2
• Gene: Itgbn / 35368
• FlyBaseID: FBgn0010395
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: XP_006522991.1
• Gene: Itgb2l / 16415
• MGIID: 1277979
• Length: 795
• Species: Mus musculus
• Alignment Length: 760
• Identity: 199/760 - (26%)
• Similarity: 332/760 - (43%)
• Gaps: 120/760 - (15%)

  Fly    35 HADSCERCLSAHLECAWC-----TDKEYQVGYRCLSRRQLLNYNCSETDIYENQPVLDVLQDKPL 94
            :..:|:.|:.:...||||     |.:......||.:..|||...|:...:.:.:.:.:..:||
Mouse    29 NVSTCQDCIRSGPSCAWCQKLNFTGRGEPDSVRCDTPEQLLLKGCTSEYLVDPKSLAESQEDK-- 91

  Fly    95 KDYETSDQAVQVTPQRAYLKLVKGNTQRMKLSYRTARNNPLDLYVLMDLTWTMRDDKKTLEELGA 159
                ..||. |::|:...:.|..|.....|:.::..::|.:|||.||.|:.:.:.....::.||:
Mouse    92 ----ERDQR-QLSPRNVTVFLRPGQAATFKVDFQRTQDNSVDLYFLMGLSGSAQGHLSNVQTLGS 151

  Fly   160 QLSQTLKNLTGNYRLGFGSFADKPTLPMILPQHRENPCAAERATCEPTYGYRHQLSLTDDIPAFT 224
            .|.:.|..::.:.|:||||..:..                          ::|.|.||.|...|.
Mouse   152 DLLKALNEISRSGRIGFGSIVNMT--------------------------FQHILKLTADSSQFQ 190

  Fly   225 SAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQARKVVILVTDGFMHLAGDGLLAGIIQRN 289
            ..:....::|.|...:|.|||::||.:|..||||:...| .::||||...|||.|..|......:
Mouse   191 RELRKQLVSGKLATPKGQLDAVVQVAICLGEIGWRNGTR-FLVLVTDNDFHLAKDKTLGTRQNTS 254

  Fly   290 DKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEEVVSSYWELSALMKEISYVDIL 354
            |.:|||:. |.|......||.|:.::..:|....|..||.|...:|.:|.:|:..:.::: :..|
Mouse   255 DGRCHLDD-GMYRSRGEPDYQSVVQLASKLAENNIQPIFVVPSRMVKTYEKLTTFIPKLT-IGEL 317

  Fly   355 SADSSNILELIKKSYESLIKRTQFADNS-PDFIDMAYYTDC--GGQFPSLQKRNYCNNVTLGKQI 416
            |.||||:.:||:.:|..|........:: |..:.:.|.:.|  |...|. :....|:.|.:..|:
Mouse   318 SDDSSNVAQLIRNAYSKLSSIVVLNHSTIPSILKVTYDSYCSNGTSNPG-KPSGDCSGVQINDQV 381

  Fly   417 DFYVDVTLKKYPDNQVYTHKIRVEETSLSEFMD-LDVELQRPCPCQETPDPENEEGRFLCDYKGY 480
            .|.|::|..:....|.:.       .....||| :.|.:...|.||   ..|..:...||..||.
Mouse   382 TFQVNITASECFREQFFF-------IQALGFMDSVTVRVLPLCECQ---CQEQSQHHSLCGGKGA 436

  Fly   481 LYCGMCECDEGWTGTYCNCPTDATNVTSNEALLQKCRQPFSDKSTSELVCSNHGDCDCGTCLC-- 543
            :.||:|.|:.|:.|..|.|.|..   .|::.|...||     |..|.::||..|||.||.|.|
Mouse   437 MECGICRCNSGYAGKNCECQTQG---PSSQDLEGSCR-----KDNSSIMCSGLGDCICGQCECHT 493

  Fly   544 ----DPGYTGPFCECRECLDCDE---------KLADCFCGQCVCKYGWSGSKCNCDGDTDACVGP 595
                :....|.:|||.. ::|:.         :...|.||:|.|:||:.||.|.|...|..|:..
Mouse   494 SDIPNKEIYGQYCECNN-VNCERYDGQVCGGPERGHCSCGRCFCRYGFVGSACQCRMSTSGCLNN 557

  Fly   596 TGEICSERGTCQCEECQCEEPYLGKFCEIDPEKDNKLCLFYEPCVTCLIEQKQGMGVCENLTEIC 660
            ....||..|.|.|..|.|:..|....||..|...:: |..|..|..||.:.
Mouse   558 RMVECSGHGRCYCNRCLCDPGYQPPLCEKRPGYFHR-CSEYYSCARCLKDN-------------- 607

  Fly   661 SSLDRQETYPYNFVHELDPEQDQCLVRLVNKHGIQC-DSFFVYQVIDHSNFLTI---QAVDCEPP 721
            |::..:|.  :|.:....|..::..:...:..|  | .::.:||. |.|:..:|   :::.|
Mouse   608 SAIKCREC--WNLLFSNTPFSNKTCMTERDSEG--CWTTYTLYQP-DQSDINSIYIKESLVC--- 664

  Fly   722 DYVALVGYISAFTLLIG------LLIIFIILW-YIRAKDAREYAK 759
                  ..||..|:|:|      |.:||:::: .:..|..::.||
Mouse   665 ------AEISNTTILLGVIVGVLLAVIFLLVYCMVYLKGTQKAAK 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Itgbn	NP_523608.2	INB	38..460	CDD:197563	111/430 (26%)
		EGF_2	529..552	CDD:400365	10/28 (36%)
		Integrin_b_cyt	752..785	CDD:462580	3/8 (38%)
Itgb2l	XP_006522991.1	vWFA	32..419	CDD:469594	111/430 (26%)
		I-EGF_1	417..448	CDD:465729	12/33 (36%)