Protein Alignment Itgbn and itgb5

DIOPT Version :10

• Sequence 1: NP_523608.2
• Gene: Itgbn / 35368
• FlyBaseID: FBgn0010395
• Length: 799
• Species: Drosophila melanogaster
• Sequence 2: NP_001135704.1
• Gene: itgb5 / 100216279
• XenbaseID: XB-GENE-6455199
• Length: 807
• Species: Xenopus tropicalis
• Alignment Length: 795
• Identity: 251/795 - (31%)
• Similarity: 397/795 - (49%)
• Gaps: 81/795 - (10%)

  Fly    38 SCERCLSAHLECAWCTDKEY----QVGYRCLSRRQLLNYNCSETDIYENQPVLDVLQDKPLKDYE 98
            ||::||..|.:||||:.:|:    .|..||.....|::..|.:..|......:.|:::.||...|
 Frog    43 SCQQCLVTHPQCAWCSQEEFGGSSTVTSRCDFAHNLISRGCKKEFIEGPGSTVTVIKNLPLSTKE 107

  Fly    99 TSDQA---VQVTPQRAYLKLVKGNTQRMKLSYRTARNNPLDLYVLMDLTWTMRDDKKTLEELGAQ 160
            :|...   :||.||:..|.|..|.....|:..|...:.|:|||.||||:.:|:||..|:..||..
 Frog   108 SSSSQTNFIQVAPQKISLSLRPGAAASFKVQVRQVEDYPVDLYYLMDLSLSMKDDLNTIRNLGTI 172

  Fly   161 LSQTLKNLTGNYRLGFGSFADKPTLPM--ILPQHRENPCAAER--ATCEPTYGYRHQLSLTDDIP 221
            |:..:|.||.|:|||||||.||...|.  ..|:::.|||...:  ..|.|::|:||.|||||...
 Frog   173 LAAEMKKLTSNFRLGFGSFVDKNISPFSYTAPKYQNNPCTGYKYSPVCVPSFGFRHLLSLTDKTN 237

  Fly   222 AFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQARKVVILVTDGFMHLAGDGLLAGII 286
            :|.:.|...:::.|.|..||..||::|..||...|||:::|..::::.|||..|:|.||.|||::
 Frog   238 SFNAEVQKQRVSRNRDAPEGAFDAILQAAVCGDRIGWRKEASHLLVITTDGVPHIALDGKLAGLV 302

  Fly   287 QRNDKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEEVVSSYWELSALMKEISYV 351
            |.:|.:||||:..||:.|...|||||..:..:|....||:|||||......|...:||:...: .
 Frog   303 QPHDGRCHLNEDNEYSASDQLDYPSLALLGEKLSENNINLIFAVTNSHYVLYKNFTALIPGTT-A 366

  Fly   352 DILSADSSNILELIKKSYESLIKRTQF-ADNSPDFIDMAYYTDC--GGQFPSLQKRNYCNNVTLG 413
            :||..||.||:::|..:|.::..:.:. ...||:.:.:::...|  |...|.::|   |.::.:|
 Frog   367 EILDQDSQNIIQVIVSAYNNIRSKVELTVSESPEDLSLSFTATCQDGSSHPGVKK---CGDLKIG 428

  Fly   414 KQIDFYVDVTLKKYP---DNQVYTHKIRVEETSLSEFMDLDVELQRPCPCQETPDPENEEGRFLC 475
            ..:.|.|.|..:..|   ..|.:|    ::.....:.:::.|.....|.|.:..:|.:.:    |
 Frog   429 DTVSFEVSVEARSCPPPGTEQTFT----IKPVGFRDSLEVTVTYNCSCSCAQQGEPASSK----C 485

  Fly   476 DYKGYLYCGMCECDEGWTGTYCNCPTD--ATNVTSNEALLQKCRQPFSDKSTSELVCSNHGDCDC 538
            ...|...||:|||:.|:.|..|.|..:  :::||.|     .||:     :..:.||:..|.|.|
 Frog   486 SGNGTYTCGVCECEAGFLGGRCQCGEEELSSDVTQN-----TCRE-----AEGKTVCNGRGRCLC 540

  Fly   539 GTCLCDPG----YTGPFCECRE--CLDCDEKL----ADCFCGQCVCKYGWSGSKCNCDGDTDACV 593
            |.|:|...    .:|.||:|.:  |......|    .:|.||:|.|..|:.|..|||..:|..|:
 Frog   541 GLCVCYQSEFGLISGSFCQCDDFSCARYKGALCSGHGECDCGECKCHAGYIGDNCNCTIETATCL 605

  Fly   594 GPTGEICSERGTCQCEECQCEEP-YLGKFCEIDPEKDNKLCLFYEPCVTCLIEQKQGMGVCENLT 657
            ...|::||.:|.|.|..|||.|| ..|:.||..|...: .|.....|:.|.:.|...:  .:|.|
 Frog   606 SDDGQMCSGKGNCVCGRCQCIEPGAFGETCEKCPTCPD-ACGTKRDCIECRLYQTGQL--ADNQT 667

  Fly   658 EICSSLDRQETYPYNFVHELD---PEQDQCLVRLVNKHGIQCDSFFVY-QVIDHSNFLTIQAVDC 718
              |..|.:.|...   |.|||   ||...|:.:..:    .|...|.| :....|....::..:|
 Frog   668 --CQKLCKDEIVT---VEELDTDNPEAAVCIYKTES----DCVMRFTYSEESGRSVLRVLKEPEC 723

  Fly   719 -EPPD----YVALVGYISAFTLLIGLLIIFIILWYIRAKDAREYAKFEEDQKNSVRQE---NPIY 775
             ..||    .:|:||.|    |||||:::.:....:...|.||:::| :.::...|.|   ||:|
 Frog   724 ASAPDTLTVLLAVVGSI----LLIGLVLLAVWKLLVTIHDRREFSRF-QSERTRARYEMASNPLY 783

  Fly   776 RDPVGRYEVPKALSV 790
            |..|..:.|.:..|:
 Frog   784 RPAVSTHNVDEMYSM 798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Itgbn	NP_523608.2	INB	38..460	CDD:197563	147/438 (34%)
		EGF_2	529..552	CDD:400365	9/26 (35%)
		Integrin_b_cyt	752..785	CDD:462580	11/35 (31%)
itgb5	NP_001135704.1	INB	43..472	CDD:197563	146/436 (33%)
		I-EGF_1	474..502	CDD:465729	9/31 (29%)
		Integrin_B_tail	645..727	CDD:462325	21/92 (23%)
		Integrin_b_cyt	755..791	CDD:462580	11/36 (31%)