Protein Alignment CG9270 and Abcc9

DIOPT Version :10

• Sequence 1: NP_995741.2
• Gene: CG9270 / 35366
• FlyBaseID: FBgn0032908
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_035641.1
• Gene: Abcc9 / 20928
• MGIID: 1352630
• Length: 1546
• Species: Mus musculus
• Alignment Length: 1321
• Identity: 410/1321 - (31%)
• Similarity: 667/1321 - (50%)
• Gaps: 155/1321 - (11%)

  Fly    43 YNALKEHKAETLGDKFFATWQSEVRSCGDSPKKEPSIIRVILKVFGWQLFL-------------- 93
            |..|||            .::.:.:...|.|.:.|||...:.:.||..:.|
Mouse   261 YVCLKE------------AYEEQKKKAADHPNRTPSIWLAMYRAFGRPILLSSTFRYLADLLGFA 313

  Fly    94 -----SGIVVGVLEL--GTRATLPLILGALIAEFTRNGNGDGLWAQIYGLTLILSILFSVLMFHP 151
                 ||||..|.|.  .||...|..|.:  .||..|       |.:..:.|.|:::........
Mouse   314 GPLCISGIVQRVNEKTNTTREMFPETLSS--KEFLEN-------AHVLAVLLFLALILQRTFLQA 369

  Fly   152 LMMGLMHLAMKMRVAVSTAIYRKALRLSRT--ALGDTTTGQVVNLISNDLGRFDRALIHFHF--- 211
            .....:...:.:|.|:...||.|.||||.:  ::|:.|.||:.||::.:..:    |:.|.|
Mouse   370 SYYVTIETGINLRGALLAMIYNKILRLSTSNLSMGEMTLGQINNLVAIETNQ----LMWFLFLCP 430

  Fly   212 -LWLGPLELLISSYFLYQQIGVASLYGIVILLLFLPIQTFLSRLTSRLRHQTALRTDQRVRMMNE 275
             ||..|:::::....||..:|.::|.|..:::|..|||.|::...:..:..|...:.:|::..||
Mouse   431 NLWAMPVQIIMGVILLYNLLGSSALVGAAVIVLLAPIQYFIATKLAEAQKSTLDYSTERLKKTNE 495

  Fly   276 IISGIQVIKMYTWEKPFGRLIERLRRSEMSSIRKVNYIRGTLLSFEITLSRIAIFVSLLGFV--- 337
            |:.||:::|:|.||..|.:.:|..|..|:||::  .:...|.||..:. :.|.|...|..||
Mouse   496 ILKGIKLLKLYAWEHIFCKSVEETRMKELSSLK--TFALYTSLSIFMN-AAIPIAAVLATFVTHA 557

  Fly   338 -LMGGELTAERAFSVTAFYNILRRTVCKFFPSGMSQFA-EMMVTLRRIKGFMMRSETEALYLKGG 400
             ..|..|....||:..:.::||...:  |..|.:.:|| :.:::::::..|::..|......:.|
Mouse   558 YASGNNLKPAEAFASLSLFHILVTPL--FLLSTVVRFAVKAIISVQKLNEFLLSDEIGEDSWRAG 620

  Fly   401 QTNKLFE---------GEPLVKLQSFQARWNHDHVE----------------------------P 428
            :....||         .:|:.:.|  ..|::.|..|                            .
Mouse   621 EGTLPFESCKKHTGVQSKPINRKQ--PGRYHLDSYEQARRLRPAETEDIAIKVTNGYFSWGSGLA 683

  Fly   429 VLENINISLSPPQLVAVIGPVGSGKSSLIQAILGELPGESGKL-----------------KVQGD 476
            .|.||:|.:...||..::|.||.|||||:.|||||:....||:                 :.:..
Mouse   684 TLSNIDIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVYWNNVNESEPSFEATRSRSRYS 748

  Fly   477 ISYASQEPWLFNASVRDNILFGLPMDKHRYRNVIRNCALERDFELL-HGDRTFVGERGASLSGGQ 540
            ::||:|:|||.||:|.:||.||.|.::.||:.|...|:|:.|.:|| .||:|.:||||.:|||||
Mouse   749 VAYAAQKPWLLNATVEENITFGSPFNRQRYKAVTDACSLQPDIDLLPFGDQTEIGERGINLSGGQ 813

  Fly   541 RARISLARAVYRQADTYLLDDPLSAVDTHVGRHLFEECMRGFLRD--KLVILVTHQLQFLEHADL 603
            |.||.:|||:|:..:...||||.||:|.|:..||.:|.:..||:|  :.|:||||:||:|.|||.
Mouse   814 RQRICVARALYQNTNIVFLDDPFSALDIHLSDHLMQEGILKFLQDDKRTVVLVTHKLQYLTHADW 878

  Fly   604 IVIMDKGKISAVGTYEEMLKSGQDFGKLLATEAQEMGD-----SNQEQVNAEGDSRNDKSTYSRQ 663
            |:.|..|.:...||.::           :.|:..|:.:     .|::....|.|...|::|..|:
Mouse   879 IIAMKDGSVLREGTLKD-----------IQTKDVELYEHWKTLMNRQDQELEKDMEADQTTLERK 932

  Fly   664 S------SRVSRVSVTSVDSSTESILDNERQPAQESRSQGKIGLGIYGKYFSAGSGWLMVILVAF 722
            :      ||.::..:...|...|...|.|...:...|.:.|:.......|.::| |:.::.|:.|
Mouse   933 TLRRAMYSREAKAQMEDEDEEEEEEEDEEDNMSTVMRLRTKMPWKTCWWYLTSG-GFFLLFLMIF 996

  Fly   723 FCLGTQILASGGDYFLSYWVK----NNDSSSSTDIYI--FSGINAALVIFALLRTLLFFSMAMHS 781
            ..|....:....||:|:.|..    |:...:....|:  ||.:..|.:...|:.:|....|.:.:
Mouse   997 SKLLKHSVIVAIDYWLATWTSEYSINHPGKADQTFYVAGFSILCGAGIFLCLVTSLTVEWMGLTA 1061

  Fly   782 STQLHNTMFQGVSRTALYFFHANPSGRILNRFAMDLGQVDEILPAVMLDCIQIFLTISGIIGVLC 846
            :..||:.:...:....:.||...|.|.|||||:.|...:|:.:|..:....:..|.....||::.
Mouse  1062 AKNLHHNLLNKIILGPIRFFDTTPLGLILNRFSADTNIIDQHIPPTLESLTRSTLLCLSAIGMIS 1126

  Fly   847 ITNPWYLINTITMFLAFHFLRTFYLSTSRDLKRLEAIARSPMYSHFSATLNGLSTIRAMEAQDLL 911
            ...|.:|:....:.:||:|::.::...|:||:.|:...:.|:..|||.|..||:||||...:...
Mouse  1127 YATPVFLVALAPLGVAFYFIQKYFRVASKDLQELDDSTQLPLLCHFSETAEGLTTIRAFRHETRF 1191

  Fly   912 TKEYDNYQDIHSSGYYTFLSTNRAFGYYLDLFCVAYVISVTLMSYFNPPVDNPGQIGLVITQAMS 976
            .:......|.::..|....:.||......|......|::.::.|....  .|.|.:||.:..|::
Mouse  1192 KQRMLELTDTNNIAYLFLSAANRWLEVRTDYLGACIVLTASIASISGS--SNSGLVGLGLLYALT 1254

  Fly   977 MTGTVQWGMRQSAELENSMTSVERVLEYRHLEAEGEFESPDDKKPPMNWPQEGLISAEQLSLRYN 1041
            :|..:.|.:|..|:||..|.:|::|..:..:|:|....:.|..:.|.:|||||.|....|.:||.
Mouse  1255 ITNYLNWVVRNLADLEVQMGAVKKVNSFLTMESENYEGTMDPSQVPEHWPQEGEIKIHDLCVRYE 1319

  Fly  1042 PDPKADRVLKSLNFIIMPREKIGIVGRTGAGKSSLINALFRL-SYNEGSLVIDNTDILGIGLHDL 1105
            .:.|.  |||.:...|.|.:|:||.||||:|||||..|.||: ...:|.:|||..||..:.||.|
Mouse  1320 NNLKP--VLKHVKAYIKPGQKVGICGRTGSGKSSLSLAFFRMVDIFDGKIVIDGIDISKLPLHTL 1382

  Fly  1106 RSKISIIPQEPVLFSGTLRCNLDPFEQYADEKLWEALEEVHLKDEVSELPNGLESVVAEGGSNYS 1170
            ||::|||.|:|:||||::|.||||..:..|::||||||...||:.|..||.||::.|.|||.|:|
Mouse  1383 RSRLSIILQDPILFSGSIRFNLDPECKCTDDRLWEALEIAQLKNMVKSLPGGLDATVTEGGENFS 1447

  Fly  1171 VGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQSTIRRKFRDCTVLTIAHRLNTIIDSDR 1235
            ||||||.|||||.:|::.||:||||||::|..|:.::|..:...|.|.||:|||||::||:.:|.
Mouse  1448 VGQRQLFCLARAFVRKSSILIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILTADL 1512

  Fly  1236 VMVLDAGTLVEFGSPFELLTQ 1256
            |:|:..|.::|:.:|..||.|
Mouse  1513 VIVMKRGNILEYDTPESLLAQ 1533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9270	NP_995741.2	PLN03130	10..1289	CDD:215595	410/1321 (31%)
Abcc9	NP_035641.1	MRP_assoc_pro	23..1543	CDD:188098	410/1321 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	941..964		5/22 (23%)