Protein Alignment CG9270 and haf-8

DIOPT Version :9

• Sequence 1: NP_995741.2
• Gene: CG9270 / 35366
• FlyBaseID: FBgn0032908
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_502776.1
• Gene: haf-8 / 190369
• WormBaseID: WBGene00001818
• Length: 633
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 131/545 - (24%)
• Similarity: 254/545 - (46%)
• Gaps: 61/545 - (11%)

  Fly   756 FSGINAALVIFALL-------RTLLFFSMAMHSSTQLHN---TMFQGVSRTALYFFHANPSGRIL 810
            |..|..|.::.||:       ::..:|.|.........|   .:|:.:....:.||..|.:|:::
 Worm    91 FDIIKRACLLLALIQFSEATCKSACYFFMQYAEKLTARNIRIQLFRSILHQEISFFDENKTGQLV 155

  Fly   811 NRFAMDLGQVDEILPAVMLDCI--QIFLTISGIIGVLCITNPWYLINTITMFLAFH---FLRTFY 870
            :|...|...:...|| |.::.:  .:|:....|..:.|.:  |.|  |:|.|:.|.   .:..:|
 Worm   156 SRITHDSESISNTLP-VHIETLVNNLFMFFGSIPIMFCYS--WQL--TLTSFIEFPITLLMTRYY 215

  Fly   871 LSTSRDLKRLEAIARSPMYSHFSATLNGLSTIRAMEAQDLLTKEY-DNYQDIHSSGYYTFLSTNR 934
            ......|...|..|.:.........|:.:.|:|:..|::...|.| .|.:|     ::...:...
 Worm   216 GLAVEKLSEKENDATAASNETVEEVLSAIRTVRSFAAENFEQKRYTKNTED-----WFKISTKTV 275

  Fly   935 AFGYYLDLFCVAYVISVTLMSYFNPPVDNPGQI---GLVITQAMSMTGTVQWGMRQSAELENSMT 996
            ..|...:.|....:.|..::.|.     ..|.:   |.:..:|:.......|.:..:....:|:.
 Worm   276 TLGTIYNYFWALMLRSQDVIRYL-----YGGYLALNGRMAPEALLTFIFYHWRLHTAINAFSSLF 335

  Fly   997 S-VERVL----EYRHLEAEGEFESPDDKKPPMNW------PQ-EGLISAEQLSLRYNPDPKADRV 1049
            | |.:.:    :..||         .::||.:::      |: :|.|..|.:...| |..|...|
 Worm   336 SGVMKTIGLSRKVIHL---------INRKPQLDYDFGTETPEIQGKIEFEVVEFAY-PTRKTVNV 390

  Fly  1050 LKSLNFIIMPREKIGIVGRTGAGKSSLINALFRLSY--NEGSLVIDNTDILGIGLHDLRSKISII 1112
            :..:|..|...:.:.:||.:|.|||:|: :|.:..|  ..|.::.|...|..|......|.|:::
 Worm   391 INGINLSIESGKTVALVGPSGNGKSTLV-SLIQQFYTPQSGRILTDGIPIQNINHQHYHSNIALV 454

  Fly  1113 PQEPVLFSGTLRCN-LDPFEQYADEKLWEALEEVHLKDEVSELPNGLESVVAEGGSNYSVGQRQL 1176
            .|||.|||||:|.| |...|...:|.:.:|.|..::.:.||::.:|.::...|.|...|.||:|.
 Worm   455 AQEPTLFSGTIRENILFGIENGTEEAMLKAAEMANVHEFVSKMDDGYDTKCGEKGVQMSGGQKQR 519

  Fly  1177 VCLARAILRENRILVMDEATANVDPQTDALIQSTIRRKFRDCTVLTIAHRLNTIIDSDRVMVLDA 1241
            :.:|||::|..|:|::||||:.:|.:::.::|..:.:..::.||:.|||||:|:..:.::.|::.
 Worm   520 IAIARALIRNPRVLILDEATSALDSESEGMVQEALNKCAKERTVIVIAHRLSTVRKAQKIAVIEN 584

  Fly  1242 GTLVEFGSPFELLTQSWSKVFYGMV 1266
            |::.|.|...||: ::...::|.:|
 Worm   585 GSVKEMGCHDELM-ENQDGLYYKLV 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9270	NP_995741.2	CFTR_protein	6..1257	CDD:273530	129/534 (24%)
		ABC_membrane	92..362	CDD:294371
		ABCC_MRP_domain1	412..611	CDD:213217
		ABC_membrane	718..981	CDD:294371	46/243 (19%)
		ABCC_MRP_domain2	1029..1250	CDD:213211	72/223 (32%)
haf-8	NP_502776.1	MdlB	42..613	CDD:224055	131/545 (24%)
		ABC_membrane	63..318	CDD:279056	46/241 (19%)
		ABC_MTABC3_MDL1_MDL2	373..611	CDD:213216	75/239 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000