Protein Alignment CG9270 and mrp-1

DIOPT Version :10

• Sequence 1: NP_995741.2
• Gene: CG9270 / 35366
• FlyBaseID: FBgn0032908
• Length: 1292
• Species: Drosophila melanogaster
• Sequence 2: NP_508122.2
• Gene: mrp-1 / 180409
• WormBaseID: WBGene00003407
• Length: 1534
• Species: Caenorhabditis elegans
• Alignment Length: 1355
• Identity: 479/1355 - (35%)
• Similarity: 729/1355 - (53%)
• Gaps: 134/1355 - (9%)

  Fly    10 PRESAGIFSTLMFCFALPILFKGRKKTLEPTDLYNALKEHKAETLGDKFFATWQSEVRSC----- 69
            |..:|...:.|.|.:...:.:.|.||:||..||::..:..|||.:...|......||...
 Worm   208 PEYTASFLNQLTFQWFSGLAYLGNKKSLEKEDLWDLNERDKAENIIPSFIENLIPEVEGYRRKIK 272

  Fly    70 ----GDSPKKEPSIIRVILKVFGWQLFLSGIVVGVLELGTRATLPLILGALIAEFTRNGNGDGLW 130
                ...||..|||:..|.|.:.:.|...|....:.:| .:...|.:|..||: |..:.| ..:|
 Worm   273 KNPEAAIPKNHPSILIPIFKTYKFTLLAGGCYKLMFDL-LQFVAPELLRQLIS-FIEDKN-QPMW 334

  Fly   131 AQI-YGLTLILSILFSVLMFHPLMMGLMHLAMKMRVAVSTAIYRKALRLSRTALGDTTTGQVVNL 194
            ..: ..|.:.||.|...::.|.....:..|.|.:|..:::|:|.|.|.||..|....|||.:|||
 Worm   335 IGVSIALLMFLSSLLQSMILHQYFHEMFRLGMNIRSVLTSAVYTKTLNLSNEARKGKTTGAIVNL 399

  Fly   195 ISNDLGRFDRALIHFHFLWLGPLELLISSYFLYQQIGVASLYGIVILLLFLPIQTFLSRLTSRLR 259
            :|.|:.|...........|..||::|:|.|||::.:||:.|.|.|||:|.:|..:|:|......:
 Worm   400 MSVDIQRIQDMTTFIMLFWSAPLQILLSLYFLWKLLGVSVLAGFVILILLIPFNSFISVKMRNCQ 464

  Fly   260 HQTALRTDQRVRMMNEIISGIQVIKMYTWEKPFGRLIERLRRSEMSSIRKVNYIR-GTLLSFEIT 323
            .:.....|:|::||:||::|::|:|:|:|||...:::..:|..|:..::|::|:. .|.||:...
 Worm   465 MEQMKFKDERIKMMSEILNGMKVLKLYSWEKSMEKMVLEVREKEIRVLKKLSYLNAATTLSWACA 529

  Fly   324 LSRIAIFVSLLGFVLMGGE---LTAERAFSVTAFYNILRRTVCKFFPSGM-----SQFAEMMVTL 380
            ...:|:....| :||...|   ||.:..|...|.:||||      ||..:     ||..:...:.
 Worm   530 PFLVAVLTFGL-YVLWDPENNVLTPQITFVALALFNILR------FPLAVFAMVFSQAVQCSASN 587

  Fly   381 RRIKGFMMRSETEALYLKGGQTNKLFEG-EPLVKLQSFQARWNHDHVEPVLENINISLSPPQLVA 444
            .|:|.|....|...      ||:..:.| :..:|:......|.....:..|.:|..::...||||
 Worm   588 TRLKEFFAAEEMSP------QTSIAYGGTDSAIKMDGGSFAWGSKEEDRKLHDITFNIKRGQLVA 646

  Fly   445 VIGPVGSGKSSLIQAILGELPGESGKLKVQGDISYASQEPWLFNASVRDNILFGLPMDKHRYRNV 509
            ::|.||||||||:.|:|||:...||.::|.|.::|..|..|:.|.|:|:||||..|.|...|:||
 Worm   647 IVGRVGSGKSSLLHALLGEMNKLSGSVQVNGSVAYVPQLAWIQNLSLRNNILFNRPYDAKLYQNV 711

  Fly   510 IRNCALERDFELLHG-DRTFVGERGASLSGGQRARISLARAVYRQADTYLLDDPLSAVDTHVGRH 573
            |.||||.:|.|.|.. |||.:||:|.:|||||:.|:|||||||:.|:..||||||||||:|||:|
 Worm   712 IENCALVQDLESLPAEDRTEIGEKGINLSGGQKQRVSLARAVYQNAEIVLLDDPLSAVDSHVGKH 776

  Fly   574 LFEECM---RGFLRDKLVILVTHQLQFLEHADLIVIMDKGKISAVGTYEEMLKSGQDFG----KL 631
            :||..:   .|.|..|..:|:||.|.:|:|.|.::::....||.:|||:|::.|...|.    :.
 Worm   777 IFENVISTATGCLGTKTRVLLTHGLTYLKHCDQVIVLKDETISEMGTYQELMNSNGAFSEFLEEF 841

  Fly   632 LATEAQEMG-------DSN--------------------QEQVNAEGDSRNDKSTYSRQSS--RV 667
            |..|::..|       ||.                    |.|::.|.:..:||:....::.  :.
 Worm   842 LLEESKHKGRSVSFGEDSKEVNELLRDLDQVSPAIRQRIQSQMSQEIEKTDDKNAEIIRNGLHKD 906

  Fly   668 SRVSVTSVDSS--TESIL------DNERQPAQESRSQ---------GKIGLGIYGKYFSAGSGWL 715
            .:.:.:|:..|  .||:|      :...:|.:::::|         ||:...:|..||.|..  :
 Worm   907 EQTAHSSIGKSEEKESLLGAISPKEKTPEPPKQTKTQLIEKEAVETGKVKFEVYMSYFRAIG--I 969

  Fly   716 MVILVAFFC-LGTQILASGGDYFLSYW--------VKNNDSSSSTD----IYIFSGIN------A 761
            .:.||.|.. :.:.:|....:.:|:.|        :..|.|||.|.    ||...|:.      |
 Worm   970 KIALVFFLVYVASSMLGVFSNLYLARWSDDAKEIALSGNGSSSETQIRLGIYAVLGMGQATSVCA 1034

  Fly   762 ALVIFALLRTLLFFSMAMHSSTQLHNTMFQGVSRTALYFFHANPSGRILNRFAMDLGQVDEILPA 826
            |.:|.||       .|.. :|..||.|:.:.:.|:.:.||...|.|||||||..|:..:|..||:
 Worm  1035 ASIIMAL-------GMVC-ASRLLHATLLENIMRSPMAFFDVTPLGRILNRFGKDIDVIDYRLPS 1091

  Fly   827 VMLDCIQIFLTISGIIGVLCITNPWYLINTITMFLAFHFLRTFYLSTSRDLKRLEAIARSPMYSH 891
            .::..:...:....|..|.....|........:.:.::||..||:||||.|||||:.:|||:|||
 Worm  1092 CIMTFVGAIVQAVTIFAVPIYATPLSSFPITIVLIGYYFLLRFYVSTSRQLKRLESASRSPIYSH 1156

  Fly   892 FSATLNGLSTIRAMEAQDLLTKEYDNYQDIHSSGYYTFLSTNRAFGYYLDLFCVAYVI-SVTLMS 955
            |..::.|.|:|||....|...:|..:..|.:.:.||..:..||.....|::.....|: |.....
 Worm  1157 FQESIQGASSIRAYGVVDKFIRESQHRVDENLATYYPSIVANRWLAVRLEMVGNLIVLSSAGAAV 1221

  Fly   956 YFNPPVDNP----GQIGLVITQAMSMTGTVQWGMRQSAELENSMTSVERVLEYRHLEAEGEFESP 1016
            ||.   |:|    |.:||.::.|:::|.|:.|.:|.::|||.::.:|||:.||.....||   :.
 Worm  1222 YFR---DSPGLSAGLVGLSVSYALNITQTLNWAVRMTSELETNIVAVERINEYTITPTEG---NN 1280

  Fly  1017 DDKKPPMNWPQEGLISAEQLSLRYNPDPKADRVLKSLNFIIMPREKIGIVGRTGAGKSSLINALF 1081
            .....|.:||:.|.||.:..|:||.|.  .|.||..:...|.|.||||||||||||||||..|||
 Worm  1281 SQSLAPKSWPENGEISIKNFSVRYRPG--LDLVLHGVTAHISPCEKIGIVGRTGAGKSSLTLALF 1343

  Fly  1082 RLSYNEGSLV-IDNTDILGIGLHDLRSKISIIPQEPVLFSGTLRCNLDPFEQYADEKLWEALEEV 1145
            |:...:|..: ||.|:|..:.|..|||:::|:||:|||||||:|.|||||..::|:::||||...
 Worm  1344 RIIEADGGCIEIDGTNIADLLLEQLRSRLTIVPQDPVLFSGTMRMNLDPFFAFSDDQIWEALRNA 1408

  Fly  1146 HLKDEVSELPNGLESVVAEGGSNYSVGQRQLVCLARAILRENRILVMDEATANVDPQTDALIQST 1210
            ||...|..|..||...::|||.|.|||||||:|||||:||:.::||:|||.|.||.:||:|:|.|
 Worm  1409 HLDSFVKSLQEGLHHHISEGGENLSVGQRQLICLARALLRKTKVLVLDEAAAAVDVETDSLLQKT 1473

  Fly  1211 IRRKFRDCTVLTIAHRLNTIIDSDRVMVLDAGTLVEFGSPFELLTQSWSKVFYGM 1265
            ||.:|:|||||||||||||::||||::|||.|.:.||.:|.:||:.. ..:||.|
 Worm  1474 IREQFKDCTVLTIAHRLNTVMDSDRLLVLDKGCVAEFDTPKKLLSNP-DGIFYSM 1527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9270	NP_995741.2	PLN03130	10..1289	CDD:215595	479/1355 (35%)
mrp-1	NP_508122.2	MRP_assoc_pro	23..1531	CDD:188098	479/1355 (35%)