DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9272 and NTH2

DIOPT Version :9

Sequence 1:	NP_610078.2	Gene:	CG9272 / 35365	FlyBaseID:	FBgn0032907	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_973767.1	Gene:	NTH2 / 837100	AraportID:	AT1G05900	Length:	386	Species:	Arabidopsis thaliana

Alignment Length:	361	Identity:	138/361 - (38%)
Similarity:	190/361 - (52%)	Gaps:	53/361 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 SAGAAGSSSSVFFSPVQTRKQRLLNGEAVKKTNIKMEPLSPARVAPKKFRKDDRMVTRVQMGSAT 110
            |..|.|:|.|.  :.|..||:|:...:        :||:........|.|||
plant    49 SEAAHGASESE--TRVSLRKKRIKQDD--------LEPVKKCSARETKARKD------------- 90

  Fly   111 VVICKVVPDAVDSPV---------RVDKIREEVEPQIKQEAPEDSPSFSEVQA-----PHPLWFN 161
              :|. :||..|||.         |..|:...:      ::.|.|||.|.::.     |...|..
plant    91 --MCG-LPDIEDSPYKKTNGTASSRTRKLNSYI------KSTEASPSASSIKTAGLGIPPENWEK 146

  Fly   162 HLENIRIMRNSRTAPVDTMGCHRCADLKADSKTQRFQNLVALMLSSQTKDQTTYEAMNRLKDRG- 225
            .||.||.|:.|..|||:.:.|.|.... ...|.:||..|:..:||||||:..|..|:.||...|
plant   147 VLEGIRKMKPSEEAPVNAVECDRTGSF-LPPKERRFYVLIGTLLSSQTKEHITGAAVERLHQNGL 210

  Fly   226 LTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDKYGSDIPDNVKDLVALPGVGPKMAH 290
            |||..:.:...:.::.|::||.||..||..:|:..:|...:|..|||..:::|::|||||||:||
plant   211 LTPEAIDKADESTIKELIYPVGFYTRKATNVKKVAKICLMEYDGDIPRTLEELLSLPGVGPKIAH 275

  Fly   291 ICMAVAWNKITGIGVDVHVHRLSNRLGWVPKP-----TKEPEQTRVALEKWLPFSLWSEVNHLFV 350
            :.:.||||.:.||.||.||||:.||||||.||     |..||:|||||::|||...|..:|.|.|
plant   276 LVLHVAWNDVQGICVDTHVHRICNRLGWVSKPGTKQKTSSPEETRVALQQWLPKGEWVAINFLLV 340

  Fly   351 GFGQTICTPVKPNCGECLNKDICPSAHAETKEKRKK 386
            |||||||||::|:||.|...:|||||..||.....|
plant   341 GFGQTICTPLRPHCGTCSITEICPSAFKETPSTSSK 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9272	NP_610078.2	Nth	169..376	CDD:223255	99/212 (47%)
		ENDO3c	205..355	CDD:214684	75/155 (48%)
		FES	356..376	CDD:197771	11/19 (58%)
NTH2	NP_973767.1	Nth	180..369	CDD:223255	93/188 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	128	1.000	Domainoid score	I1734
eggNOG	1	0.900	-	-		E1_COG0177
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	225	1.000	Inparanoid score	I1176
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1322642at2759
OrthoFinder	1	1.000	-	-		FOG0003205
OrthoInspector	1	1.000	-	-		otm2760
orthoMCL	1	0.900	-	-		OOG6_100563
Panther	1	1.100	-	-	LDO	PTHR43286
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2154
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830