DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9272 and nth1

DIOPT Version :9

Sequence 1:	NP_610078.2	Gene:	CG9272 / 35365	FlyBaseID:	FBgn0032907	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_593210.1	Gene:	nth1 / 2543510	PomBaseID:	SPAC30D11.07	Length:	355	Species:	Schizosaccharomyces pombe

Alignment Length:	240	Identity:	116/240 - (48%)
Similarity:	141/240 - (58%)	Gaps:	12/240 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   155 PHPLWFNHLENIRIMRNSRTAPVDTMGCHRCADLKADSKTQRFQNLVALMLSSQTKDQTTYEAMN 219
            |...|....:.|..|:....||||..|||...: :.|.|..|||.||||||||||||......|.
pombe     8 PPENWREVYDEICKMKAKVVAPVDVQGCHTLGE-RNDPKKFRFQTLVALMLSSQTKDIVLGPTMR 71

  Fly   220 RLKDR---GLTPLKVKEMPVTELENLLHPVSFYKNKAKYLKQTVEILTDKYGSDIPDNVKDLVAL 281
            .||::   ||....::.:....|..|:..|.|:..|..||||...||::|:..||||.|:||:.|
pombe    72 NLKEKLAGGLCLEDIQNIDEVSLNKLIEKVGFHNRKTIYLKQMARILSEKFQGDIPDTVEDLMTL 136

  Fly   282 PGVGPKMAHICMAVAWNKITGIGVDVHVHRLSNRLGWVPKPTKEPEQTRVALEKWLPFSLWSEVN 346
            |||||||.::||::||||..||||||||||:.|.|.|.  .||..||||.||:.|||..||.|:|
pombe   137 PGVGPKMGYLCMSIAWNKTVGIGVDVHVHRICNLLHWC--NTKTEEQTRAALQSWLPKELWFELN 199

  Fly   347 HLFVGFGQTICTPVKPNCGECL--NKDICPSAHAE----TKEKRK 385
            |..||||||||.|....|..|.  :|.:||||..|    |..|||
pombe   200 HTLVGFGQTICLPRGRRCDMCTLSSKGLCPSAFKEKSGITITKRK 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9272	NP_610078.2	Nth	169..376	CDD:223255	106/211 (50%)
		ENDO3c	205..355	CDD:214684	78/152 (51%)
		FES	356..376	CDD:197771	8/21 (38%)
nth1	NP_593210.1	Nth	21..236	CDD:223255	109/217 (50%)
nth1	NP_593210.1	ENDO3c	57..208	CDD:214684	78/152 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	142	1.000	Domainoid score	I1189
eggNOG	1	0.900	-	-		E1_COG0177
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1897
Inparanoid	1	1.050	209	1.000	Inparanoid score	I958
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003205
OrthoInspector	1	1.000	-	-		oto101089
orthoMCL	1	0.900	-	-		OOG6_100563
Panther	1	1.100	-	-	LDO	PTHR43286
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R847
SonicParanoid	1	1.000	-	-		X2154
TreeFam	1	0.960	-	-
	13	12.850