DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RPA2 and RPA2

DIOPT Version :9

Sequence 1:	NP_001260652.1	Gene:	RPA2 / 35364	FlyBaseID:	FBgn0032906	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_001118376.1	Gene:	RPA2 / 816985	AraportID:	AT2G24490	Length:	279	Species:	Arabidopsis thaliana

Alignment Length:	279	Identity:	66/279 - (23%)
Similarity:	123/279 - (44%)	Gaps:	52/279 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NDSF--GDFNATQ-----TAPTGAASNQKGEGIVPLVVKQIVD-----APEGNIELFGMQYAMAC 54
            |..|  |.|.::|     .:.:..|.|:..:|:||:.||||.:     ..:..:.:.|:......
plant    10 NSGFSGGGFMSSQPSQAYESSSSTAKNRDFQGLVPVTVKQITECFQSSGEKSGLVINGISLTNVS 74

  Fly    55 VVAIVRNVETSS-TKITYTLEDHSGRIDAHYWLEEG-DALKAPEVMVNNYVKVYGTTRSQGGSKT 117
            :|.:|.:.:.|. |::.:||:|.:||||...|:.|. ||.:...|....||::.|..::..|...
plant    75 LVGLVCDKDESKVTEVRFTLDDGTGRIDCKRWVSETFDAREMESVRDGTYVRLSGHLKTFQGKTQ 139

  Fly   118 LMIFKLLPVLDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIADFTASQSSAIVSG 182
            |::|.:.|::|.|||..|.:|.::...:..:.|.:              .:.|.|.|.::....|
plant   140 LLVFSVRPIMDFNEVTFHYIECIHFYSQNSESQRQ--------------QVGDVTQSVNTTFQGG 190

  Fly   183 LEPKQQAVFQAIKSNVSEEGISRKEL---------------KAKFSHISD---------SELTNI 223
            ....|..:...:.|:.:.:|..||.|               :.:..||.:         ::|..:
plant   191 SNTNQATLLNPVVSSQNNDGNGRKNLDDMILDYLKQPACTARQQGIHIDEIAQQLKIPKNKLEGV 255

  Fly   224 LDFMISEGHIYSSIDADHF 242
            :..:..:|.|||:||..||
plant   256 VQSLEGDGLIYSTIDEYHF 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RPA2	NP_001260652.1	RFA2	12..246	CDD:227560	62/267 (23%)
		RPA2_DBD_D	52..144	CDD:239924	29/93 (31%)
		RPA_C	<182..238	CDD:285937	14/79 (18%)
RPA2	NP_001118376.1	RPA2_DBD_D	72..165	CDD:239924	28/94 (30%)
RPA2	NP_001118376.1	RPA_C	163..272	CDD:400920	21/112 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5235
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37712
Inparanoid	1	1.050	79	1.000	Inparanoid score	I2383
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D924826at2759
OrthoFinder	1	1.000	-	-		FOG0003638
OrthoInspector	1	1.000	-	-		otm3452
orthoMCL	1	0.900	-	-		OOG6_102423
Panther	1	1.100	-	-	O	PTHR13989
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.830