DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RPA2 and rpa2

DIOPT Version :9

Sequence 1:	NP_001260652.1	Gene:	RPA2 / 35364	FlyBaseID:	FBgn0032906	Length:	246	Species:	Drosophila melanogaster
Sequence 2:	NP_001006795.1	Gene:	rpa2 / 448500	XenbaseID:	XB-GENE-487430	Length:	275	Species:	Xenopus tropicalis

Alignment Length:	253	Identity:	81/253 - (32%)
Similarity:	134/253 - (52%)	Gaps:	20/253 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 GDFNATQTAPTGA--ASNQKGEGIVPLVVKQIVDAPEGNIELFGM---QYAMACVVAIVRNVETS 65
            |.|.:  .|||..  .|..:.:.|||..|.|::.|.: |.|:|.:   :.:...:|.|||:.|.:
Frog    27 GGFGS--PAPTQGEKKSRSRSQQIVPCTVSQLLSATQ-NDEMFRIGEAELSQVTIVGIVRHAEKA 88

  Fly    66 STKITYTLEDHSGR-IDAHYWLEEGDALKAPEVMV---NNYVKVYGTTRSQGGSKTLMIFKLLPV 126
            .|.|.|.::|.:.. :|...|::..:|  :.|.||   .:||||.|..||....|:::.||:.||
Frog    89 PTNILYKVDDMTAAPMDVRQWVDTDEA--SCENMVVPPGSYVKVAGHLRSFQNKKSVVAFKIAPV 151

  Fly   127 LDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIAD----FTASQSSAIVSGLEPKQ 187
            .|.||..:|:|||::|........:..|.|: |.|.:..|.:.|    |:....:| .:||.|.|
Frog   152 DDMNEFVSHMLEVVHAHMTMNSQGAPSGGGS-AVALNTPGRLGDSGGAFSGGNDNA-TNGLTPHQ 214

  Fly   188 QAVFQAIKSNVSEEGISRKELKAKFSHISDSELTNILDFMISEGHIYSSIDADHFICT 245
            ..:...|||....||::.:|||.:...::.:.:...:||:.:||||||::|.:|:..|
Frog   215 SQILNLIKSFKGNEGMAFEELKNRLHGMNVNTIRQAVDFLSNEGHIYSTVDDEHYKST 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RPA2	NP_001260652.1	RFA2	12..246	CDD:227560	79/247 (32%)
		RPA2_DBD_D	52..144	CDD:239924	35/95 (37%)
		RPA_C	<182..238	CDD:285937	20/55 (36%)
rpa2	NP_001006795.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	23..47		6/21 (29%)
		RFA2	27..272	CDD:227560	80/251 (32%)
		RPA2_DBD_D	75..169	CDD:239924	35/95 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9576
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37712
Inparanoid	1	1.050	112	1.000	Inparanoid score	I4721
OMA	1	1.010	-	-		QHG58029
OrthoDB	1	1.010	-	-		D561832at33208
OrthoFinder	1	1.000	-	-		FOG0003638
OrthoInspector	1	1.000	-	-		otm49518
Panther	1	1.100	-	-	LDO	PTHR13989
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1086
SonicParanoid	1	1.000	-	-		X4625
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110