Protein Alignment RPA2 and RPA4

DIOPT Version :10

• Sequence 1: NP_610077.1
• Gene: RPA2 / 35364
• FlyBaseID: FBgn0288834
• Length: 246
• Species: Drosophila melanogaster
• Sequence 2: NP_037479.1
• Gene: RPA4 / 29935
• HGNCID: 30305
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 63/257 - (24%)
• Similarity: 113/257 - (43%)
• Gaps: 25/257 - (9%)

  Fly     4 SFGDFNATQTAPTG-----------AASNQKG----EGIVPLVVKQIVDAP--EGNIELFGMQYA 51
            |:|..:|...|..|           |...|:.    :.:||..|.|::.:.  :...::.|:..:
Human     8 SYGSISAADGASGGSDQLCERDATPAIKTQRPKVRIQDVVPCNVNQLLSSTVFDPVFKVRGIIVS 72

  Fly    52 MACVVAIVRNVETSSTKITYTLEDHSGR-IDAHYWLEEGDALKAPEVMVNNYVKVYGTTRSQGGS 115
            ...:|.::|..|.:|..|.|.::|.:.: |:|..|.......:...:.|..||||:|..:...|:
Human    73 QVSIVGVIRGAEKASNHICYKIDDMTAKPIEARQWFGREKVKQVTPLSVGVYVKVFGILKCPTGT 137

  Fly   116 KTLMIFKLLPVLDPNEVCTHLLEVLNARYRAEDYQSKGGAGAGAGASSGSGSIADFTASQSSAIV 180
            |:|.:.|:..:.|.||...|:||.:||....:..:......:...:.|......|...|..:.|
Human   138 KSLEVLKIHVLEDMNEFTVHILETVNAHMMLDKARRDTTVESVPVSPSEVNDAGDNDESHRNFI- 201

  Fly   181 SGLEPKQQAVFQAIKSNVSEEGISRKELKAKFSHISDSELTNILDFMISEGHIYSSIDADHF 242
                  |..|.:.|.....:||.|..||:|:...:|...:...:|::..|||||.::|.:||
Human   202 ------QDEVLRLIHECPHQEGKSIHELRAQLCDLSVKAIKEAIDYLTVEGHIYPTVDREHF 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RPA2	NP_610077.1	RFA2	12..246	CDD:227560	60/249 (24%)
		RPA2_DBD_D	52..144	CDD:239924	28/92 (30%)
RPA4	NP_037479.1	RFA2	32..259	CDD:227560	58/233 (25%)
		RPA2_DBD_D	73..166	CDD:239924	28/92 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	175..194		2/18 (11%)