Protein Alignment Mtp and dsc-4

DIOPT Version :9

• Sequence 1: NP_610075.2
• Gene: Mtp / 35362
• FlyBaseID: FBgn0266369
• Length: 886
• Species: Drosophila melanogaster
• Sequence 2: NP_499903.3
• Gene: dsc-4 / 176852
• WormBaseID: WBGene00001099
• Length: 892
• Species: Caenorhabditis elegans
• Alignment Length: 1003
• Identity: 198/1003 - (19%)
• Similarity: 355/1003 - (35%)
• Gaps: 255/1003 - (25%)

  Fly    10 RTLLLLALFLGLLEDGKTALIAPNSQQIFK---------LQNQVILQELGRDSSSAETSYTFETD 65
            |..||||:.:|:      .|..|:..:|.|         .:||..:.|  ......:..|.|.|:
 Worm     5 RIWLLLAVTVGV------CLAVPDLDEIKKNLRKHGPDYYKNQPKMNE--NTVRLLKVDYWFRTE 61

  Fly    66 LKI-----------NSVWSGD----------EDQLLEVF-ISGSKVDASGKARSITRIPDRPFYI 108
            ..|           ::|.:|:          |..:|..| ::....|..|.        ..|.||
 Worm    62 SMIYDDIDNKEKDPSTVIAGNFSFETLHHDVEGGMLGRFTLTQCNTDNCGN--------PSPIYI 118

  Fly   109 SLVRG--QPDKVIAHTSKDQSLLNLERGIASLLQLRLDASQEEELDVS---GLCRVSYNVKSSTK 168
            :..:|  ..:.::..:.:..:..|....|.:.:....:..:.:|..|.   |.|.|::......:
 Worm   119 AFRQGGNNAEHILKASDESDATWNFLYAIVNTIYTPAEYGEGDEQTVDTIYGRCFVNFGRPEDKR 183

  Fly   169 VEKTKRDCSLWDLRVNYNPEEALGVTQQAQETVFY----------------ELSSEGTLLH---- 213
            ..:....|.| ....|:...|.:...|..|: |:|                |:.:..:.||
 Worm   184 FRRIIEKCDL-GYGTNFTKFEGIESVQYDQD-VWYTQNTKVDADIIMVDAIEMLAFKSPLHEKYG 246

  Fly   214 --AESQENHRLNLAAKPDVGSFVKSSL------------------ILQHVSQGSEEVKQLQLGSL 258
              .||:.:..:....:..|.|:...::                  :.:||     ::.|.|...|
 Worm   247 FTLESRTHVEITNRTRVFVTSYCNDTVPSAKCAEQAFGAVRVGGKLYEHV-----KIAQEQSNKL 306

  Fly   259 DKAIQSLLEWYRVFELESDVDGMISAIKEQTLEDQLKASLTELQSADVGKSSLALAYVKLIPLAR 323
            .|    |:..||                 :.|:|...:.:.|..|         |.|.::...||
 Worm   307 TK----LIGTYR-----------------RHLQDMGDSHICEKHS---------LLYSQIAQEAR 341

  Fly   324 ITRQEQFEDLL--TEHAEVLPQLVDLLGAVQTFDAHNATFGFLYKESETTSEQL------DLLEK 380
            :.:::.:|..:  .|:..||..:...||.|.|            .||.||:.::      |.|:.
 Worm   342 LAKRQDWEAAIQYPENDHVLSLIASALGGVGT------------AESITTAREVLLTASPDYLDD 394

  Fly   381 YLQSLAVATHPDRKIVEHL---FGLLEQESIKKHLKLRESVIQTVATLTRQ------SGLDVEDP 436
            .|..::.::..:.|..:.|   .|.|:::| :::.|    |..|:||:..:      |.|:..:.
 Worm   395 LLFGISQSSSNNEKWHKQLMYWLGSLDKKS-EEYWK----VANTIATVLNKRCEASTSSLNSCNK 454

  Fly   437 LLKEVRSYLLQGLTSKEPTL-YIRALQNLQDPATIEALLEHAQTGEAPNLSVAALQALKAFPLGS 500
            ..:.:.:..:..||:....: .:..|:|:....:.....:.....|:.::..|||..:.|.....
 Worm   455 GKETIVNKFITDLTAGGVEVRVLEVLENIPIFGSYTFAKKFICETESEDVQKAALNVILAASKNL 519

  Fly   501 FNS--SHRL--QFESIFYQRKRRFDSSARTLALDIILSLRPTQEQLGNFL---DYLASNDRQFEI 558
            :.:  :|:|  .|.:...|..   .:|...||:||:|...|..:.:...:   :.|..:|::
 Worm   520 YETQLTHKLIKLFRNTCSQET---PTSHSQLAIDILLKCVPDHQNVATLILRTETLNPDDQE--- 578

  Fly   559 KTYVLQKL--------RMLAEKCPRFR--ALFKSELVKR-----RHVNNYNVLGQKGLTTVLTRQ 608
            |.:.|.|.        .:.||...|.|  .:|:...:.|     .||:...:
 Worm   579 KWHYLYKAIEASGNKDELKAEFWSRMRKFKVFRPNFLHRALQADSHVHWQEI------------- 630

  Fly   609 LSQAPAFNETLLST--QEVYQGILKRGSVEFLLHAGRSQASSFKLGIYTAGLGSLV-GDGDSGDG 670
               |.|.|..|.||  .|..|...||...|..:..||.:.:.|.|.|.|..|...| |...|..|
 Worm   631 ---ADASNFQLFSTANTEFLQKSFKRSIFELSMKKGRKEHNLFSLSIDTEHLEQFVTGSASSRSG 692

  Fly   671 NDAIPADDEFSEDEAVTAGMEISVQGAQLRPLVFFSGQTELMGHVWGGSASDST-PAYQATTLSQ 734
                          |....:.|.|.|.:|.....|.|.|:|:..||  .|...| .|::.....:
 Worm   693 --------------APQGSVRIGVAGHKLPTHHIFKGSTDLLSTVW--EADGRTHKAFEGHVPVR 741

  Fly   735 DNEHYIILTSGATLHWRVLGARSVDLNGKVGFSLWNRNAQTEIQQNTGSAVLGHLAVG-FTYAKL 798
            |....:.|.||.||....:||.|:.:......||||:.:..:.:..|..::  ||... :.:::.
 Worm   742 DVRLSVPLLSGLTLDVDSVGAISMRVLASAEVSLWNQRSNAKAEAYTSGSL--HLTASLYHHSEP 804

  Fly   799 VQDFSITHEPKLSLNAD---------LDFYSGIKLCMQLQRPEQLLKQTNVRSVFLQSVDRPYAK 854
            |:....|.....:...|         .||      |::.......:.|..|       |.....|
 Worm   805 VRHVESTISALSTFTTDTRAIFETLPYDF------CLRTSNSNVDINQKTV-------VQDQIGK 856

  Fly   855 HVRSTLSHKTA--GCTFALNQKNNEMCN 880
            |.:.||:.|..  |.|:.|:......||
 Worm   857 HKKKTLNRKRVHPGVTYRLDDSTIRQCN 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mtp	NP_610075.2	LPD_N	38..567	CDD:214755	110/637 (17%)
dsc-4	NP_499903.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159782
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4337
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	57	1.000	Inparanoid score	I4039
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45382
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006503
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108584
Panther	1	1.100	-	-	LDO	PTHR13024
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.800