Protein Alignment Cyp11b3 and Cyp12d1-d

DIOPT Version :9

• Sequence 1: NP_861545.1
• Gene: Cyp11b3 / 353498
• RGDID: 727886
• Length: 498
• Species: Rattus norvegicus
• Sequence 2: NP_995812.1
• Gene: Cyp12d1-d / 2768720
• FlyBaseID: FBgn0053503
• Length: 521
• Species: Drosophila melanogaster
• Alignment Length: 523
• Identity: 124/523 - (23%)
• Similarity: 225/523 - (43%)
• Gaps: 92/523 - (17%)

  Rat    25 STATQAPKTLKPFEAIPQYSRNKWLKMIQILREQSQENLHLEMHQAFQELGPIFRHSA--GGAQI 87
            |:.|:..||   ::.||:.::.|:::......|....::........:..|.|:....  |....
  Fly    33 SSITEEHKT---YDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDW 94

  Rat    88 VSVMLPEDAEKLHQVESILPRRMTLESWVAHRE-----LRGLRRGVFLLNGADWRFNRLQLNPNM 147
            |:....:|.|.:.:.|.|.|||..|:|.|..||     :.|..:|:.......|...|..:||..
  Fly    95 VTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIF 159

  Rat   148 LSPKAVQSFVPFVDVVARDFVENLKKRMLENVHGSMSMDIQSNVFNYTMEASHFVISGERLGLTG 212
            :.|:.::.:...:..:..:|:|.:|:     :....::::..   ::|.|.|..|.  |.|||..
  Fly   160 MQPRGLRMYYEPLSNINNEFIERIKE-----IRDPKTLEVPE---DFTDEISRLVF--ESLGLVA 214

  Rat   213 HDL----------NPESLKFIHALHSMFKSTTQLMFLPKNLTRWTSTQVWKGHFESWDIISEYVT 267
            .|.          |.::|........:|:.|.:|...|                ..|.|||
  Fly   215 FDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQP----------------SMWKIIS---- 259

  Rat   268 KCIKNVYRELAEGRQQSWSVISEMVAQSTLSM-------DAIHANSM-----------------E 308
               ...||::......|.:|..:|:.::..::       :.|::|||                 :
  Fly   260 ---TPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLD 321

  Rat   309 LIAGSVDTTAISLVMTLFELARNPDVQQALRQESLA---AEASIAANPQKAMSDLPLLRAALKET 370
            ::...||.||..|...|..|:::||.|..||:|.|:   .:.|:.  .::.|.|:|.|||.:|||
  Fly   322 ILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLL--NEENMKDMPYLRAVIKET 384

  Rat   371 LRLYPIGSSLERIVDSDLVLQNYHVPAGTLVIIYLYSMGRNPAVFPRPERYMPQRWLERKRS--- 432
            ||.||.|....|...:|::|..|.||.||.|::....:.:....:|||:.::|:|||....:
  Fly   385 LRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKK 449

  Rat   433 -----FQHLAFGFGVRQCLGRRLAEVEVLLLLHHMLKIFQVETLRQEDVQMAYRFVLMPNPRLVL 492
                 |..|.||||.|.|:|:|:.::|:...:..:::.|.||..|  |....::.:.:..|.:..
  Fly   450 MQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNR--DASRPFKTMFLMEPAITF 512

  Rat   493 TIR 495
            ..:
  Fly   513 PFK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp11b3	NP_861545.1	p450	41..494	CDD:278495	119/504 (24%)
Cyp12d1-d	NP_995812.1	p450	70..508	CDD:299894	115/474 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0159
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D185685at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820