DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31673 and SPCC364.07

DIOPT Version :9

Sequence 1:	NP_724294.1	Gene:	CG31673 / 35348	FlyBaseID:	FBgn0051673	Length:	326	Species:	Drosophila melanogaster
Sequence 2:	NP_587837.1	Gene:	SPCC364.07 / 2539490	PomBaseID:	SPCC364.07	Length:	466	Species:	Schizosaccharomyces pombe

Alignment Length:	327	Identity:	86/327 - (26%)
Similarity:	147/327 - (44%)	Gaps:	44/327 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ATRAFKVLISHPNVPAPALELLRSRGAETIICQSVPPSRDEILQKVPGVDAIYWAHYQPLNAGIL 68
            |:...|:|:.. ||...||..|:..|.:....:: ..|.|::::|:.||.||.......|...:|
pombe    52 ASEDIKILLLE-NVNQSALSNLKDEGYQVEFLKT-SMSEDDLVEKIKGVHAIGIRSKTRLTRRVL 114

  Fly    69 DAAGSQL----RCVSTMSSGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRHFHAG 129
            :||.|.:    .|:.|....:||.     .:|||.:.::|.....:||:|.||.:|:..|.....
pombe   115 EAADSLIVIGCFCIGTNQVDLDFA-----AERGIAVFNSPYANSRSVAELVIGYIISLARQVGDR 174

  Fly   130 RTEIERSQW-KIEQINWMMGQEIRDSVIGFFGFGGI-------SQAIAKRLQCWDVAKIIYHTRT 186
            ..|:.|.:| |:....|    |||...:|..|:|.|       ::|:...:..:|:..|:.....
pombe   175 SLELHRGEWNKVSSGCW----EIRGKTLGIIGYGHIGSQLSVLAEAMGLHVVYYDILPIMPLGSA 235

  Fly   187 RKENDGDFKAEHVSFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLVNQT 251
            ::.:         |..:||..:||:.:..|.:.||:...:.|.|..||..|..:|.:||.:|:..
pombe   236 KQLS---------SLPELLHRADFVSLHVPASPETKNMISSKEFAAMKEGSYLINASRGTVVDIP 291

  Fly   252 DLHDALTNGTISAAGLDVTTPEPL------------PANSPLLNVPNCVILPHMGTQTMKTTIEM 304
            .|.||..:|.|:.|.:||...||.            ...|.|.:..|.::.||:|..|.:....:
pombe   292 ALVDASKSGKIAGAAIDVYPSEPAGNGKDKFVDSLNSWTSELTHCKNIILTPHIGGSTEEAQYNI 356

  Fly   305 GL 306
            |:
pombe   357 GI 358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31673	NP_724294.1	LdhA	9..320	CDD:223980	85/322 (26%)
CG31673	NP_724294.1	GDH	9..318	CDD:240626	85/322 (26%)
SPCC364.07	NP_587837.1	PRK11790	54..466	CDD:236985	85/325 (26%)
		PGDH_3	56..367	CDD:240653	85/323 (26%)
		ACT_3PGDH	396..465	CDD:153173
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53501
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880