Protein Alignment CG31673 and CTBP2

DIOPT Version :10

• Sequence 1: NP_724294.1
• Gene: CG31673 / 35348
• FlyBaseID: FBgn0051673
• Length: 326
• Species: Drosophila melanogaster
• Sequence 2: NP_073713.2
• Gene: CTBP2 / 1488
• HGNCID: 2495
• Length: 985
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 92/338 - (27%)
• Similarity: 136/338 - (40%)
• Gaps: 43/338 - (12%)

  Fly    11 LISHPNVPAPALELLRSRG-----------AETIICQSVPPSRDEILQKV--PGVDAIYWAHYQP 62
            :::.|..|.|.:.||..|.           |....|.:  .|..||.:||  ..|.|:.: |...
Human   565 IMNGPLHPRPLVALLDGRDCTVEMPILKDLATVAFCDA--QSTQEIHEKVLNEAVGAMMY-HTIT 626

  Fly    63 LNAGILDAAGSQLRCVSTMSSGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRHFH 127
            |....|:.. ..||.:..:.||.|.|||....:.||.:.:.|.......||..|..::...|
Human   627 LTREDLEKF-KALRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYR--- 687

  Fly   128 AGRTEIERSQW------------KIEQINWMM--GQEIRDSVIGFFGFGGISQAIAKRLQCWDVA 178
                   |:.|            .:|||..:.  ...||...:|..|||...||:|.|.:.:..:
Human   688 -------RNTWLYQALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFS 745

  Fly   179 KIIYHTRTRKENDGDFKAEHV-SFEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNV 242
            .|.|....:...:.....:.| :.:.||.:||.:.:...|........|......|::.:..||.
Human   746 VIFYDPYLQDGIERSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNA 810

  Fly   243 ARGGLVNQTDLHDALTNGTISAAGLDVTTPEPLP-ANSPLLNVPNCVILPHMGTQTMKTTIEMGL 306
            ||||||::..|..||..|.|..|.|||...||.. |..||.:.||.:..||....:.:.::||..
Human   811 ARGGLVDEKALAQALKEGRIRGAALDVHESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMRE 875

  Fly   307 LAANNILNAIEGK 319
            .||..|..||.|:
Human   876 AAATEIRRAITGR 888

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31673	NP_724294.1	GDH	9..318	CDD:240626	91/335 (27%)
CTBP2	NP_073713.2	PHA03247	<109..572	CDD:223021	1/6 (17%)
		PHA03377	<363..575	CDD:177614	2/9 (22%)
		CtBP_dh	574..892	CDD:240624	90/329 (27%)