DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG31673 and CTBP1

DIOPT Version :9

Sequence 1:NP_724294.1 Gene:CG31673 / 35348 FlyBaseID:FBgn0051673 Length:326 Species:Drosophila melanogaster
Sequence 2:NP_001364115.1 Gene:CTBP1 / 1487 HGNCID:2494 Length:441 Species:Homo sapiens


Alignment Length:332 Identity:94/332 - (28%)
Similarity:137/332 - (41%) Gaps:31/332 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 LISHPNVPAPALELLRSRG-----------AETIICQSVPPSRDEILQKV--PGVDAIYWAHYQP 62
            :::.|..|.|.:.||..|.           |....|.:  .|..||.:||  ..|.|:.: |...
Human    19 IMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDA--QSTQEIHEKVLNEAVGALMY-HTIT 80

  Fly    63 LNAGILDAAGSQLRCVSTMSSGIDFVDIPEFQKRGIPLGHTPGVVKNAVADLAIGLMIAAGRH-- 125
            |....|:.. ..||.:..:.||.|.:||......||.:.:.|.......||..:..::...|.  
Human    81 LTREDLEKF-KALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRAT 144

  Fly   126 -FHAGRTEIERSQWKIEQINWMM--GQEIRDSVIGFFGFGGISQAIAKRLQCWDVAKIIYHTRTR 187
             .|....|..|.| .:|||..:.  ...||...:|..|.|.:.||:|.|.:.:....:.|.... 
Human   145 WLHQALREGTRVQ-SVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYL- 207

  Fly   188 KENDGDFKA---EHVS-FEQLLQESDFLVVAAPLTNETREKFNGKAFNLMKRSSVFVNVARGGLV 248
              :||..:|   :.|| .:.||..||.:.:...|........|......|::.:..||.||||||
Human   208 --SDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTARGGLV 270

  Fly   249 NQTDLHDALTNGTISAAGLDVTTPEPLP-ANSPLLNVPNCVILPHMGTQTMKTTIEMGLLAANNI 312
            ::..|..||..|.|..|.|||...||.. :..||.:.||.:..||....:.:.:|||...||..|
Human   271 DEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREI 335

  Fly   313 LNAIEGK 319
            ..||.|:
Human   336 RRAITGR 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG31673NP_724294.1 LdhA 9..320 CDD:223980 94/332 (28%)
GDH 9..318 CDD:240626 93/329 (28%)
CTBP1NP_001364115.1 Interaction with GLIS2 1. /evidence=ECO:0000250 1..70 13/52 (25%)
CtBP_dh 28..346 CDD:240624 92/323 (28%)
Interaction with GLIS2 2. /evidence=ECO:0000250 288..360 20/55 (36%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 409..441
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165141270
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.840

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