Sequence 1: | NP_724288.3 | Gene: | vari / 35343 | FlyBaseID: | FBgn0250785 | Length: | 636 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001311210.1 | Gene: | CARD11 / 84433 | HGNCID: | 16393 | Length: | 1154 | Species: | Homo sapiens |
Alignment Length: | 675 | Identity: | 136/675 - (20%) |
---|---|---|---|
Similarity: | 230/675 - (34%) | Gaps: | 205/675 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 43 DLSDHDEIFLKGLLRSNSNTPHKELMLNPTEPQ-PVPLFLPAHLNNKPICDDIIRKFSPSRRLES 106
Fly 107 ---------------RELAKLLAQPHFRALLRAHDEIGALYEQRLKAAGGSTSQLEIASQR---- 152
Fly 153 QTGGYLFTE--DVLNTKMPVETIKMVGLRRDPSKPLGLT-VELDEFKQLVVARILAGGVIDKQSM 214
Fly 215 LHVGDVILEVNGTPVRTPDELQVEVSRAKE------NLTLKIGPNVDEEIKSGRYTVSGGQVKQN 273
Fly 274 GIASLETGKKLTCYMRALFTYNPSEDSLLPCRDIGLPFKSGDILQIINVKDPNWWQAKNITAESD 338
Fly 339 -KIGLIPSQEL--------------EERRKAFVAPEAD--------------YVHKIGICGTRIS 374
Fly 375 --KRKRKTMYRS-------VANCEFDK-------AELLLYEEVTRMPPFRRKTLVLIGVSGVGR- 422
Fly 423 ------------RTLKNRLINSDVDKFGAVIPHTSRPKRALEENGSSYWFMDREEMEEAVRNNE- 474
Fly 475 FLEY--GEHNGNLYGTHLQSIKDVINSGRMCIL----------DCAPN---ALKILHNSQELMP- 523
Fly 524 ------FVIFVAAPGMEQLKTIY---ADRRATGSNRN-------LSFDRQSSIRFSSRRARTLES 572
Fly 573 LASLYEDDDLVA-TVEESSFVQRKY 596 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
vari | NP_724288.3 | L27 | <105..128 | CDD:280918 | 6/37 (16%) |
PDZ_signaling | 173..250 | CDD:238492 | 16/83 (19%) | ||
SH3_MPP | 287..347 | CDD:212796 | 13/60 (22%) | ||
Guanylate_kin | 408..622 | CDD:279019 | 53/236 (22%) | ||
GuKc | 418..622 | CDD:214504 | 51/226 (23%) | ||
CARD11 | NP_001311210.1 | CARD_CARD11_CARMA1 | 22..107 | CDD:260070 | 13/53 (25%) |
Linker. /evidence=ECO:0000305|PubMed:31296852 | 111..128 | 3/16 (19%) | |||
BAR | <173..>257 | CDD:299863 | 23/113 (20%) | ||
GBP_C | <252..418 | CDD:303769 | 33/198 (17%) | ||
coiled coil | 387..398 | CDD:293879 | 1/10 (10%) | ||
coiled coil | 407..418 | CDD:293879 | 2/10 (20%) | ||
Inhibitory domain (ID). /evidence=ECO:0000303|PubMed:31296852 | 450..666 | 49/209 (23%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 460..626 | 41/180 (23%) | |||
PDZ_signaling | 680..752 | CDD:238492 | |||
SH3 | 777..839 | CDD:302595 | |||
NK | <1009..1143 | CDD:302627 | |||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0194 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |