Protein Alignment vari and mpp7a

DIOPT Version :10

• Sequence 1: NP_724288.3
• Gene: vari / 35343
• FlyBaseID: FBgn0250785
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_021335692.2
• Gene: mpp7a / 30166
• ZFINID: ZDB-GENE-991209-8
• Length: 621
• Species: Danio rerio
• Alignment Length: 604
• Identity: 186/604 - (30%)
• Similarity: 291/604 - (48%)
• Gaps: 146/604 - (24%)

  Fly   105 ESRELAKLLAQPHFRALLRAHDEIG-ALYEQRLKAAGGSTSQLEIASQRQTGGYLFTEDVLNTKM 168
            |.|||.|||::||.::||..||.:. ..|:..|..                    ..:|:.:.:.
Zfish    91 EIRELVKLLSKPHVKSLLSVHDTVAKKSYDPELPP--------------------LPDDIDDEED 135

  Fly   169 PVETIKMVGLRRDPSKPLGLTVELDEFK-QLVVARILAGGVIDKQSMLHVGDVILEVNGTPV--R 230
            .|:.|::|    ...:|||.|::.||.. .::|||||.||..|:..::||||.:.||||.||  :
Zfish   136 SVKIIRLV----KNKEPLGATIKKDEHTGAILVARILRGGAADRSGLIHVGDELKEVNGIPVDDK 196

  Fly   231 TPDELQVEVSRAKENLTLKIGPNVDEEIKSGRYTVSGGQVKQNGIASLETGKKLTCYMRALFTYN 295
            .|:|:...:|:::..:|.|:.|.:.:|.:|                     |:...:::|||.||
Zfish   197 KPEEIIRILSQSQGAITFKVVPGIKDEAQS---------------------KEPKMFIKALFDYN 240

  Fly   296 PSEDSLLPCRDIGLPFKSGDILQIINVKDPNWWQAKNITAESD---KIGLIPSQELEERRKAFVA 357
            |:||..:||::.||.||.|||||:::..|..|||||   .|.|   :.|||||:..:|||.|...
Zfish   241 PAEDKAIPCKEAGLGFKKGDILQVMSQDDATWWQAK---LEGDGNLRAGLIPSKHFQERRLAVWR 302

  Fly   358 PE------------------------------ADYVHKIGICGT----RISKRKRKT---MYRSV 385
            |.                              |.|:..:.:.|.    |:|:|.:||   ||...
Zfish   303 PTPVMTLQRTSSKRFYDDTVNCVEDIEEENEFASYLSGLHVAGLRRSFRLSRRDKKTNKSMYECK 367

  Fly   386 ANCEFDKAELLLYEEVTRMPPFRRK------TLVLIGVSGVGRRTLKNRLINSDVDKFGAVIPHT 444
            .:.::|.|::..|||||   .:|||      .:||:|.:|||...||.:|:.||...|...||||
Zfish   368 KSEQYDTADVPTYEEVT---TYRRKHGDRHRLVVLVGPTGVGLNELKRKLLISDTQHFSVTIPHT 429

  Fly   445 SRPKRALEENGSSYWFMDREEMEEAVRNNE-------------------FLEYGEHNGNLYGTHL 490
            ||.||..|..|..|.|:.:...|..::||:                   |:|:||:.||.|||..
Zfish   430 SRSKRHQESEGVEYHFISKNLFEADIQNNKKSGYSCFWRSSLPVLQRNRFIEHGEYKGNYYGTSF 494

  Fly   491 QSIKDVINSGRMCILDCAPNALKILHNSQELMPFVIFVAAPGMEQLKTIYADRRATGSNRNL--- 552
            .|::.|::..::|:||..|:.||.|..: |..|:|:||..|.:|:|       |.|..|..:
Zfish   495 DSVRSVLSKNKVCLLDVQPHTLKHLRTA-EFKPYVVFVKPPCIERL-------RETRRNAKVISG 551

  Fly   553 SFDRQSSIRFSSRRARTLESLASLYEDDDLVATVEESSFVQRKYEKYFDMVIVNEDFDETFRQVV 617
            ..|:.||..||               ::|.:..:..|..::.:|...|:.||||:|....|.::.
Zfish   552 KDDKTSSKAFS---------------EEDFLEMISASQMMENQYGHLFEKVIVNDDLTVAFSELN 601

  Fly   618 ETLDQMSHEEQWVPVNWIY 636
            :.|.::..|..|||::|.:
Zfish   602 QALKKVETEAHWVPISWTH 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vari	NP_724288.3	L27	<105..128	CDD:460717	13/22 (59%)
		PDZ_MPP6-MPP2-like	174..252	CDD:467268	30/80 (38%)
		SH3_MPP	287..347	CDD:212796	32/62 (52%)
		Guanylate_kin	408..622	CDD:395500	75/241 (31%)
mpp7a	XP_021335692.2	None