| Sequence 1: | NP_724288.3 | Gene: | vari / 35343 | FlyBaseID: | FBgn0250785 | Length: | 636 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_004078.2 | Gene: | DLG1 / 1739 | HGNCID: | 2900 | Length: | 926 | Species: | Homo sapiens |
| Alignment Length: | 665 | Identity: | 168/665 - (25%) |
|---|---|---|---|
| Similarity: | 293/665 - (44%) | Gaps: | 164/665 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 18 ELLARNNKVNGEDDTSDNA--AFRNSTDLSDHDEIFLKGLLRSNSNTPHKELMLNPTEPQPVPLF 80
Fly 81 LPAHLNN---KPICDDIIRKFSPSRRLESRELAKLLAQPHFRALLRAHDEIGALYEQRLKAAGGS 142
Fly 143 TSQLEIASQRQTGGYLFTEDVLNTKMPVETIKMVGLRRDPSKPLGLT-VELDEFKQLVVARILAG 206
Fly 207 GVIDKQSMLHVGDVILEVNGTPVR--TPDELQVEVSRAKENLTLKIGPNVDE------EIKSGRY 263
Fly 264 TVSGGQVKQNGIASLETGKKLTCYMRALFTYNPSEDSLLPCRDIGLPFKSGDILQIINVKDPNWW 328
Fly 329 QAKNIT--AESDKIGLIPSQELEERRKAFVAPEADYVHKIGICGTRISKRKRKTM-------YRS 384
Fly 385 VANCEFDKAE----------------------LLLYEEVTRMPPFRRKTLVLIGVSGVGRRTLKN 427
Fly 428 RLINSDV-----DKFGAVIPHTSRPKRALEENGSSYWFM-DREEMEEAVRNNEFLEYGEHNGNLY 486
Fly 487 GTHLQSIKDVINSGRMCILDCAPNALKILHNSQELMPFVIFVAAPGMEQLKTIYADRRATGSNRN 551
Fly 552 LSFDRQSSIRFSSRRARTLESLASLYEDDDLVATVEESSFVQRKYEKYFDMVIVNEDFDETFRQV 616
Fly 617 VETLDQMSHEEQWVP 631 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| vari | NP_724288.3 | L27 | <105..128 | CDD:280918 | 4/22 (18%) |
| PDZ_signaling | 173..250 | CDD:238492 | 22/79 (28%) | ||
| SH3_MPP | 287..347 | CDD:212796 | 33/61 (54%) | ||
| Guanylate_kin | 408..622 | CDD:279019 | 60/219 (27%) | ||
| GuKc | 418..622 | CDD:214504 | 59/209 (28%) | ||
| DLG1 | NP_004078.2 | L27_1 | 2..62 | CDD:370268 | |
| MAGUK_N_PEST | 106..223 | CDD:371162 | |||
| PDZ_signaling | 224..308 | CDD:238492 | |||
| PDZ_signaling | 317..403 | CDD:238492 | 14/52 (27%) | ||
| PDZ_assoc | 404..465 | CDD:371157 | 17/106 (16%) | ||
| PDZ | 463..547 | CDD:214570 | 23/88 (26%) | ||
| SH3_DLG1 | 582..648 | CDD:212964 | 33/67 (49%) | ||
| Guanylate_kin | 735..913 | CDD:366206 | 60/220 (27%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0194 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||