| Sequence 1: | NP_724288.3 | Gene: | vari / 35343 | FlyBaseID: | FBgn0250785 | Length: | 636 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001352629.1 | Gene: | LRGUK / 136332 | HGNCID: | 21964 | Length: | 1131 | Species: | Homo sapiens |
| Alignment Length: | 599 | Identity: | 120/599 - (20%) |
|---|---|---|---|
| Similarity: | 217/599 - (36%) | Gaps: | 166/599 - (27%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 105 ESRELAKLLAQPHFRALLRAHDEIGALYEQRLKAAGGSTSQLEIASQRQTG----------GYLF 159
Fly 160 TEDVLNTKMPVETIKMVG-----LRRDPSK-----------PLGLTV------ELDEFKQLVVAR 202
Fly 203 ILAGGVIDKQSMLHVGDVILEVNGTPVRTPDELQVEVSRAKENLTLKIGPNVDEEIKSGRYTVSG 267
Fly 268 GQVKQNGIASLETGKKLTCYMRALFTYNPSEDSLLPCRDIGLPFKSGDILQIINVKDPNWWQAKN 332
Fly 333 ITAESDKIGLI--------------PSQELEE----------------RRKAFVAPEADYVHKIG 367
Fly 368 ICGTRISKRKRKT-MYRSVANCE--FDKAELLLYEEVTRMP----PFRRKTLVLIGVSGVGRRTL 425
Fly 426 KNRLIN--SDVDKFGAVIPHTSRPKRALEENGSSYWFMDREEMEEAVRNNEFL---EYGEHNGNL 485
Fly 486 YGTHLQSIKDVINSGRMCILDCAPNALKILHNSQELMPFVIFVAAPGMEQLKTIYADRR---ATG 547
Fly 548 SNRNLSFDRQSSIRFSSRRARTLESLASLYEDDDLVATVEESSFVQRKYEKYFDMVIVNEDFDET 612
Fly 613 FRQVVETLDQMSHE 626 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| vari | NP_724288.3 | L27 | <105..128 | CDD:280918 | 7/22 (32%) |
| PDZ_signaling | 173..250 | CDD:238492 | 17/98 (17%) | ||
| SH3_MPP | 287..347 | CDD:212796 | 14/73 (19%) | ||
| Guanylate_kin | 408..622 | CDD:279019 | 49/221 (22%) | ||
| GuKc | 418..622 | CDD:214504 | 46/211 (22%) | ||
| LRGUK | NP_001352629.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 73..96 | 3/6 (50%) | |
| LRR 1 | 129..149 | 2/20 (10%) | |||
| leucine-rich repeat | 131..150 | CDD:275380 | 3/18 (17%) | ||
| LRR | <150..>337 | CDD:227223 | 38/219 (17%) | ||
| LRR 2 | 150..171 | 2/20 (10%) | |||
| leucine-rich repeat | 151..172 | CDD:275380 | 2/20 (10%) | ||
| LRR 3 | 172..193 | 2/20 (10%) | |||
| leucine-rich repeat | 173..194 | CDD:275380 | 3/20 (15%) | ||
| LRR 4 | 194..215 | 3/20 (15%) | |||
| leucine-rich repeat | 195..216 | CDD:275380 | 3/20 (15%) | ||
| LRR 5 | 216..237 | 6/29 (21%) | |||
| leucine-rich repeat | 217..238 | CDD:275380 | 6/29 (21%) | ||
| LRR 6 | 238..259 | 6/24 (25%) | |||
| leucine-rich repeat | 258..281 | CDD:275380 | 5/31 (16%) | ||
| LRR 7 | 260..280 | 5/28 (18%) | |||
| LRR 8 | 281..302 | 3/24 (13%) | |||
| leucine-rich repeat | 282..300 | CDD:275380 | 2/21 (10%) | ||
| LRR 9 | 303..324 | 8/27 (30%) | |||
| leucine-rich repeat | 304..328 | CDD:275380 | 9/30 (30%) | ||
| GMPK | 416..592 | CDD:238026 | 48/216 (22%) | ||
| Atrophin-1 | <784..1126 | CDD:331285 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG0194 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||