Protein Alignment cad and ISX

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 132
• Identity: 42/132 - (31%)
• Similarity: 65/132 - (49%)
• Gaps: 13/132 - (9%)

  Fly   256 MKKPAYPAQPQPD--LSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITI 318
            |.:|..|.:..|.  .:|...||.........|: ::|.:.|..:|..|..||||.:..:.|..:
Human    46 MDRPEGPGEEGPGEAAASGSGLEKPPKDQPQEGR-KSKRRVRTTFTTEQLHELEKIFHFTHYPDV 109

  Fly   319 RRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLH 383
            ..:|:||..::|.|.:|:|||||:|||.|||.|.|:      :|..    .||.:|...|...|.
Human   110 HIRSQLAARINLPEARVQIWFQNQRAKWRKQEKIGN------LGAP----QQLSEASVALPTNLD 164

  Fly   384 LS 385
            ::
Human   165 VA 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/54 (41%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		9/40 (23%)
		Homeodomain	83..139	CDD:459649	22/55 (40%)