Protein Alignment cad and Hoxa5

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_077365.1
• Gene: Hoxa5 / 79241
• RGDID: 620609
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 334
• Identity: 97/334 - (29%)
• Similarity: 140/334 - (41%)
• Gaps: 59/334 - (17%)

  Fly    35 NYHHTPP----NHQFL-GDVDSSHAAHHAAAAH---QMYYNSHHMFHSAAAASAGEWHSPASSTA 91
            |..|.|.    :|:.. |.:|:...|.|.::.|   ||                      :|...
  Rat    75 NRVHVPVISIIHHKLCKGAIDAQTTASHKSSTHIKKQM----------------------SSYFV 117

  Fly    92 DNFVQNVPTSA-HQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAG--GGG 153
            ::|....|... :||    |::..|:|.|.....|:|..........|..:.|:|..|:|  |.|
  Rat   118 NSFCGRYPNGPDYQL----HNYGDHSSVSEQFRDSASMHSGRYGYGYNGMDLSVGRSGSGHFGSG 178

  Fly   154 GVGGATDGGPGSAP--PNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHH----HLAHHLSA 212
            ....:...|..:||  |.:.|........||..:..|.:    ||:..|..||    .|.:...|
  Rat   179 ERARSYAAGASAAPAEPRYSQPATSTHSPPPDPLPCSAV----APSPGSDSHHGGKNSLGNSSGA 239

  Fly   213 VANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLED 277
            .||..:.:.::.....|.:....:...|:....:.|:|       .||.|||||    ..|.:..
  Rat   240 SANAGSTHISSREGVGTASAAEEDAPASSEQAGAQSEP-------SPAPPAQPQ----IYPWMRK 293

  Fly   278 LSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNR 342
            |....|..|....| :.|..||.:|.||||||:..:||:|.||:.|:|..|.|||||:|||||||
  Rat   294 LHISHDNIGGPEGK-RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNR 357

  Fly   343 RAKERKQNK 351
            |.|.:|.||
  Rat   358 RMKWKKDNK 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)
Hoxa5	NP_077365.1	Homeodomain	307..363	CDD:459649	33/56 (59%)