Protein Alignment cad and hmx3

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001072829.1
• Gene: hmx3 / 780290
• XenbaseID: XB-GENE-483776
• Length: 306
• Species: Xenopus tropicalis
• Alignment Length: 266
• Identity: 67/266 - (25%)
• Similarity: 103/266 - (38%)
• Gaps: 71/266 - (26%)

  Fly   156 GGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNN 220
            ||.|   |.:..|:  :.:..|..||   |||.|..||       .|.|.|...|.|..:.:.:.
 Frog    93 GGHT---PRTEVPD--KSLLLGPTSP---VSGGERDSP-------EPIHPLKAELEAKDSESKSP 142

  Fly   221 NN---NNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLL 282
            ..   ..:.|.....:::..                ||.|:     :..||
 Frog   143 EEIILEESEPEEGKKDDSGE----------------DWKKR-----EESPD-------------- 172

  Fly   283 DASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKER 347
               .|...|.|.|.|::..|..:||..:...||::...::.||.:|.|:|.||||||||||.|.:
 Frog   173 ---KKPCRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWK 234

  Fly   348 KQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGL-HLSHSLAHSMNPMAAMNIPA---MRLHPH 408
            :|         :...::.|:.|.....:....|.| |.:.|.|.|.:  :|.|:|.   :...||
 Frog   235 RQ---------LAAELEAANLSHAAAQRIVRVPILYHENSSSAESAS--SAANVPVSQPLLTFPH 288

  Fly   409 LAAHSH 414
            ...:||
 Frog   289 PVYYSH 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	24/54 (44%)
hmx3	NP_001072829.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	95..181		25/138 (18%)
		Homeodomain	179..235	CDD:459649	24/55 (44%)