Protein Alignment cad and Nkx6-3

DIOPT Version :9

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_083278.1
• Gene: Nkx6-3 / 74561
• MGIID: 1921811
• Length: 262
• Species: Mus musculus
• Alignment Length: 253
• Identity: 60/253 - (23%)
• Similarity: 97/253 - (38%)
• Gaps: 47/253 - (18%)

  Fly   166 APPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVAN-NNNNNNNNNNSPST 229
            :||.....:|.|.|.....:....:::|.:...:..||         ||. ...::......|..
Mouse    39 SPPGLGPQLAAGTPHGITDILSRPVATPNSSLLSGYPH---------VAGFGGLSSQGVYYGPQV 94

  Fly   230 HNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKY 294
            .:.:...|......|...:.... || :..|.|....||        .|||.:.....||.
Mouse    95 GSFSKAGNEYPTRTRNCWADTGQ-DW-RGSARPCSNTPD--------PLSDTIHKKKHTRP---- 145

  Fly   295 RVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQN---KKGSDP 356
              .:|..|...|||.:..::|:....::.||.:|.::|.|||:||||||.|.||::   ...|.|
Mouse   146 --TFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWRKKSALEPSSSTP 208

  Fly   357 NVMGVGV---------QHADYSQLL-----DAKAKLEPGLHLSHSLAHSMNPMAAMNI 400
            ...| |.         :..:|::.|     |.|.:|   |...|..|.|:..:.|.::
Mouse   209 RAPG-GASGDRAASENEDDEYNKPLDPDSDDEKIRL---LLRKHRAAFSVLSLGAHSV 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	20/51 (39%)
Nkx6-3	NP_083278.1	Homeobox	143..197	CDD:395001	22/59 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..237		7/40 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810