Protein Alignment cad and Isx

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001387929.1
• Gene: Isx / 682968
• RGDID: 1592776
• Length: 242
• Species: Rattus norvegicus
• Alignment Length: 217
• Identity: 65/217 - (29%)
• Similarity: 86/217 - (39%)
• Gaps: 61/217 - (28%)

  Fly   227 PSTHNNNNNNNSV----SNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGK 287
            |:...|.....|:    |....||.||      ::||... |||.:
  Rat    36 PTERRNLPRPQSIGGGDSRQTTTSGSK------LEKPTQD-QPQEE------------------- 74

  Fly   288 TRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            .:.|.:.|..:|..|..||||.:..:.|..|..:|:||..::|.|.:|:|||||:|||.|||.|.
  Rat    75 RKNKRRVRTTFTTEQLQELEKLFHFTHYPDIHVRSQLASRINLPEARVQIWFQNQRAKWRKQEKS 139

  Fly   353 G--SDPNVMG----------VGVQHADYSQLLD-AKAKLEPGLHLSHSLAHSMNPMAAMN--IPA 402
            |  |.|...|          :|..|.....|.| |:.||.|       ...|..|||.|.  .||
  Rat   140 GSLSAPQQPGSCTDAHCSAHIGATHRMLPPLSDSARFKLVP-------CPDSPCPMAPMGPAAPA 197

  Fly   403 MRLHPHLAAHSHSLAAVAAHSH 424
            ...||         ||:..:.|
  Rat   198 WPSHP---------AALCPYLH 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)
Isx	NP_001387929.1	Homeodomain	79..135	CDD:459649	23/55 (42%)