Protein Alignment cad and Cdx2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_076453.1
• Gene: Cdx2 / 66019
• RGDID: 621234
• Length: 310
• Species: Rattus norvegicus
• Alignment Length: 289
• Identity: 111/289 - (38%)
• Similarity: 137/289 - (47%)
• Gaps: 62/289 - (21%)

  Fly    71 MFHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGG----- 130
            |:.|:...|.|...:|     .|||     |..|......:|.|.|::::|:..|:.|.|
  Rat    13 MYPSSVRHSGGLNLAP-----QNFV-----SPPQYPDYGGYHVAAAAAAAANLDSAQSPGPSWPT 67

  Fly   131 APGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGA 195
            |.||| |.|..:....|||.....|....:||..:|...:                    |||..
  Rat    68 AYGAP-LREDWNGYAPGGAAAANAVAHGLNGGSPAAAMGY--------------------SSPAE 111

  Fly   196 PTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPS--KPPYFDWMKK 258
            ..:...||||..|..:|.:..:......|..|.      ...:.:...:.|||  :....:||:|
  Rat   112 YHAHHHPHHHPHHPAAAPSCASGLLQTLNPGPP------GPAATAAAEQLSPSGQRRNLCEWMRK 170

  Fly   259 PAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSE 323
            ||     ||.|.|..             ||||||||||||||.||||||||:..|||||||||:|
  Rat   171 PA-----QPSLGSQV-------------KTRTKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAE 217

  Fly   324 LAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            ||.||.|||||||||||||||||||.|||
  Rat   218 LAATLGLSERQVKIWFQNRRAKERKINKK 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	47/54 (87%)
Cdx2	NP_076453.1	Caudal_act	13..178	CDD:461413	52/206 (25%)
		Homeodomain	187..242	CDD:459649	47/54 (87%)