Protein Alignment cad and DRGX

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: XP_011538391.1
• Gene: DRGX / 644168
• HGNCID: 21536
• Length: 298
• Species: Homo sapiens
• Alignment Length: 244
• Identity: 51/244 - (20%)
• Similarity: 84/244 - (34%)
• Gaps: 89/244 - (36%)

  Fly   289 RTKDKYRVVYTDFQRLE-LEKEYCTSRYITIRRKSELAQTLSLSERQV----------------- 335
            |.:.:.|..:| .|:|| ||..:..:.|..:..:.|||..::|:|.:|
Human    31 RKQRRNRTTFT-LQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQLANSCLKTELQIEIND 94

  Fly   336 ------------------KIWFQNRRAKERKQNKKGSD--------------PNVMGV-----GV 363
                              ::||||||||.||..:..||              |.|..:     |.
Human    95 TIIEHSEVEDHNFSLKGARVWFQNRRAKWRKTERGASDQEPGAKEPMAEVTPPPVRNINSPPPGD 159

  Fly   364 QHADYSQLLDAKAKLE--------------PGL---------HLSHSLAHSMNPMAAMNIP---A 402
            |.....:.|:|:..|.              ||.         .|||..:....|:.:..:|   .
Human   160 QARSKKEALEAQQSLGRTVGPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMG 224

  Fly   403 MRLHPHLAAHSHSLAAVAA-------HSHQLQQQHSAQMSAAAAVGTLS 444
            :...|.....|:..|:||.       ||..:.|..:...|.:::.|.::
Human   225 LSFLPTYGCQSNRTASVATLRMKAREHSEAVLQSANLLPSTSSSPGPVA 273

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/90 (24%)
DRGX	XP_011538391.1	Homeodomain	34..125	CDD:459649	22/91 (24%)
		OAR	236..253	CDD:461067	4/16 (25%)