Protein Alignment cad and hmx2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001108570.3
• Gene: hmx2 / 555632
• ZFINID: ZDB-GENE-080506-2
• Length: 269
• Species: Danio rerio
• Alignment Length: 304
• Identity: 76/304 - (25%)
• Similarity: 114/304 - (37%)
• Gaps: 59/304 - (19%)

  Fly   118 SSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPP 182
            ::|..|||..|    .||..:.|..|| :|.:  ..||..|....|.|.|......::    |..
Zfish     2 NNSEDSGSKCS----PAPISSFTIQSI-LGTS--NDGVRSAGKDSPKSQPRKRTLSVS----SED 55

  Fly   183 ITVSGSE-----ISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNN 242
            ...:|.:     .|.||.|.|. :||..|...|.|                |.......:.:...
Zfish    56 DCSAGEDSGDCYCSEPGVPESC-NPHQPLNFCLGA----------------TKGLLPVQDGIDRR 103

  Fly   243 NRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELE 307
            ...:||..|.:   |:....|..|....|.....|..|..:.|.|.:|    |.|::..|..:||
Zfish   104 PHLTPSILPDY---KEEQGRACSQMSPVSEDRQRDGPDKQNNSAKKKT----RTVFSRSQVYQLE 161

  Fly   308 KEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLL 372
            ..:...||::...::.||.:|.|:|.|||.||||||.|.::|    ....:....:.||....|:
Zfish   162 STFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKRQ----LSAELEAANMAHASAQTLV 222

  Fly   373 DAKAKLEPGLHLSHSLAHSMNPMA----------AMNIPAMRLH 406
            ..     |.:...:||.....|.:          ..|:||:.|:
Zfish   223 GM-----PLVFRENSLLRVPVPRSIAFPTPLYYPGSNLPALPLY 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/54 (41%)
hmx2	NP_001108570.3	Homeodomain	146..202	CDD:459649	23/59 (39%)