Protein Alignment cad and crx

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001016021.1
• Gene: crx / 548775
• XenbaseID: XB-GENE-478452
• Length: 290
• Species: Xenopus tropicalis
• Alignment Length: 269
• Identity: 58/269 - (21%)
• Similarity: 95/269 - (35%)
• Gaps: 95/269 - (35%)

  Fly   255 WMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLE---LEKEYCTSRYI 316
            ::|:|.|...   .|:.:....||  |..|.|...|..|.|...|.|.|.:   ||..:..:||.
 Frog     4 YIKQPHYAVN---GLTLAGTGMDL--LHSAVGYPTTPRKQRRERTTFTRAQLDILEALFAKTRYP 63

  Fly   317 TIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPG 381
            .|..:.|:|..::|.|.:|::||:|||||.|:|.:            |....::...||.|..|.
 Frog    64 DIFMREEVALKINLPESRVQVWFKNRRAKCRQQQQ------------QSTGQAKPRPAKKKTSPA 116

  Fly   382 LHLSH---------------------------------SLAHSMNPMAAMNIPAMR--------- 404
            ...:.                                 |::...:|::|...|.|:
 Frog   117 RETNSEASTNGQYSPPPPGTAVTPSSTASATVSIWSPASISPIPDPLSAATTPCMQRSAGYPMTY 181

  Fly   405 ----------------------------LHPHLAAHSHSLAAVA-----AHSHQLQQQHSAQMSA 436
                                        :||.|:|...:|:.:|     :|..|.....|||...
 Frog   182 SQAPAYTQSYGGSSSYFTGLDCGSYLSPMHPQLSAPGATLSPIATPTMGSHLSQSPASLSAQGYG 246

  Fly   437 AAAVGTLSM 445
            |:::|..|:
 Frog   247 ASSLGFTSV 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/57 (39%)
crx	NP_001016021.1	Homeodomain	39..94	CDD:459649	21/54 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	93..144		7/62 (11%)
		TF_Otx	152..236	CDD:427350	12/83 (14%)