Protein Alignment cad and Tlx3

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001414519.1
• Gene: Tlx3 / 497881
• RGDID: 1564190
• Length: 291
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 86/378 - (22%)
• Similarity: 128/378 - (33%)
• Gaps: 127/378 - (33%)

  Fly    99 PTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGP 163
            |.||    |..|.|...:........|.....|| ||:           |..|...:||...|.|
  Rat     4 PASA----QTPHPHEPISFGIDQILNSPDQDSAP-APR-----------GPDGASYLGGPPGGRP 52

  Fly   164 GSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSA-SSPHHHLAHHLSAVANNNNNNNNNNNSP 227
            |:|.|:.....| ||.:|........::...||... ..|.|
  Rat    53 GAAYPSLPASFA-GLGAPFEDAGSYSVNLSLAPAGVIRVPAH----------------------- 93

  Fly   228 STHNNNNNNNSVSNNNRTSPS--KPPYFDWMKKPAYPAQPQ-PDLSS-----SPNLED----LSD 280
                            |..|.  .||.     ..|.||.|. |.:||     .|.:|.    :.|
  Rat    94 ----------------RPLPGAVPPPL-----PSALPAMPSVPTVSSLGGLNFPWMESSRRFVKD 137

  Fly   281 LLDASG---------------KTRTKDKYRVVYTDFQRL---ELEKEYCTSRYITIRRKSELAQT 327
            ...|:.               :.||..|.:...|.|.|:   ||||.:...:|:....::.||::
  Rat   138 RFTAAAALTPFTVTRRIGHPYQNRTPPKRKKPRTSFSRVQICELEKRFHRQKYLASAERAALAKS 202

  Fly   328 LSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSH-----S 387
            |.:::.|||.||||||.|.|:|..:..:       .:....|:|:         |.|.|     |
  Rat   203 LKMTDAQVKTWFQNRRTKWRRQTAEERE-------AERQQASRLM---------LQLQHDAFQKS 251

  Fly   388 LAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHSHQLQQQHSAQMSAAAAV 440
            |..|:.|            ..|..|:.||.|:  .:.|..::.|:::.|..::
  Rat   252 LNDSIQP------------DPLCLHNSSLFAL--QNLQPWEEDSSKVPAVTSL 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	22/57 (39%)
Tlx3	NP_001414519.1	None