Protein Alignment cad and hoxa5

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001011405.1
• Gene: hoxa5 / 496880
• XenbaseID: XB-GENE-486061
• Length: 274
• Species: Xenopus tropicalis
• Alignment Length: 346
• Identity: 87/346 - (25%)
• Similarity: 134/346 - (38%)
• Gaps: 131/346 - (37%)

  Fly    34 PNYH------HTPPNHQFLGDVDSSHAAHHAAAAHQMYYNSHHMFHSAAAASAGEWHSPASSTAD 92
            |:|.      |:..|.|: .|..|.|::.:...     ||...:....:|::    |..|:..|.
 Frog    17 PDYQLHNYGDHSSVNEQY-RDTTSMHSSRYGYG-----YNGMDLSVGRSASN----HFSANDRAR 71

  Fly    93 NFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGG 157
            |:..| |:|:.:                              |:.|:..:|
 Frog    72 NYPSN-PSSSTE------------------------------PRYNQPAAS-------------- 91

  Fly   158 ATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHH--LSAVANNNNNN 220
                 ..|.||:         |.|...|:.|.:|.              :|.  .:::.|:||..
 Frog    92 -----AHSPPPD---------PLPCTAVATSPVSD--------------SHQGGKNSITNSNNTT 128

  Fly   221 NNNNNS---PSTHNNNN--------------NNNSVSNNNRTSPS---KPPYFDWMKKPAYPAQP 265
            :|::||   .|||.|.:              :::..|:.|..||:   :|..:.||:|    ...
 Frog   129 SNSSNSSTGTSTHINRDGLGASSGAEDDAPASSDQASSQNSQSPAPSVQPQIYPWMRK----LHI 189

  Fly   266 QPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSL 330
            ..|....|           .||     :.|..||.:|.||||||:..:||:|.||:.|:|..|.|
 Frog   190 SHDNIGGP-----------EGK-----RARTAYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCL 238

  Fly   331 SERQVKIWFQNRRAKERKQNK 351
            ||||:||||||||.|.:|.||
 Frog   239 SERQIKIWFQNRRMKWKKDNK 259

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)
hoxa5	NP_001011405.1	Homeodomain	200..256	CDD:459649	33/60 (55%)