Protein Alignment cad and hoxa1

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001008017.1
• Gene: hoxa1 / 493379
• XenbaseID: XB-GENE-480737
• Length: 323
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 92/339 - (27%)
• Similarity: 131/339 - (38%)
• Gaps: 82/339 - (24%)

  Fly    68 SHHMFH--------SAAAASAGEWHSPASSTADNFV--QNVPTSAHQLMQQHHHHHAHASSSSAS 122
            |...||        .:.|.||...:|.     |.||  :.|..|:|   ..||||.|.|.....:
 Frog    24 SSRSFHPDHGITTFQSCAVSANNCNSD-----DRFVVGRGVQISSH---PHHHHHQAGAFQHHNN 80

  Fly   123 SGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSA--PPNHQQHIAEGLPSPPITV 185
            .|            ::.|::|.|..        .|..:..||.:  |.|.:..::.|.|.   :|
 Frog    81 LG------------MSYTHTSCGSN--------YGMQNFSPGYSHFPINQEADVSAGFPQ---SV 122

  Fly   186 SGSEISSPGAPTSASSPHH----------HLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVS 240
            ....|:      |:...||          |..||......|.:..|.|||..|.| .:......|
 Frog   123 YSGNIA------SSVVQHHQHQSYIEGSAHYIHHSYGPDQNISVANYNNNVSSLH-ISQREVCRS 180

  Fly   241 NNNRTSPSKPPYFDWMKKPAYPAQP----QPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDF 301
            .::.|||.....|||||....|.:.    :...:..||..                  |..:|..
 Frog   181 PSSETSPGPAQTFDWMKVKRNPPKTGKAGEYGFAGQPNTA------------------RTNFTTK 227

  Fly   302 QRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHA 366
            |..|||||:..::|:|..|:.|:|..|.|:|.||||||||||.|::|:.|:|..|..........
 Frog   228 QLTELEKEFHFNKYLTRARRVEIAAALQLNETQVKIWFQNRRMKQKKREKEGLLPISPSASTGSD 292

  Fly   367 DYSQLLDAKAKLEP 380
            :.|:.|..|:...|
 Frog   293 EKSEELSEKSNSSP 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	27/54 (50%)
hoxa1	NP_001008017.1	Homeodomain	221..274	CDD:459649	27/52 (52%)