Protein Alignment cad and MSX1

DIOPT Version :9

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 325
• Identity: 85/325 - (26%)
• Similarity: 116/325 - (35%)
• Gaps: 113/325 - (34%)

  Fly    72 FHSAAAASAGEWHSPASSTADNFVQN------------VPTSAHQLMQQHHHHHAHASSSSASSG 124
            |...|...||:..|.|::||.....:            :|.|...||..|.           ..|
Human    21 FGKPAGGGAGQAPSAAAATAAAMGADEEGAKPKVSPSLLPFSVEALMADHR-----------KPG 74

  Fly   125 SSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSE 189
            :..|..||          |.||..||             |||.|         |..||
Human    75 AKESALAP----------SEGVQAAG-------------GSAQP---------LGVPP------- 100

  Fly   190 ISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNN---NRTSPSKPP 251
             .|.|||.:.|||.                       |..|.:......:..:   ...||.||.
Human   101 -GSLGAPDAPSSPR-----------------------PLGHFSVGGLLKLPEDALVKAESPEKPE 141

  Fly   252 YFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYI 316
            ...||:.|.:  .|.|....||....|.       |.:|..|.|..:|..|.|.||:::...:|:
Human   142 RTPWMQSPRF--SPPPARRLSPPACTLR-------KHKTNRKPRTPFTTAQLLALERKFRQKQYL 197

  Fly   317 TIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQL-LDAKAKLEP 380
            :|..::|.:.:|||:|.||||||||||||.::              :|.|:..:| :.||..|.|
Human   198 SIAERAEFSSSLSLTETQVKIWFQNRRAKAKR--------------LQEAELEKLKMAAKPMLPP 248

  Fly   381  380
            Human   249  248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	25/51 (49%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		8/33 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		25/121 (21%)
		PTZ00449	<105..>248	CDD:185628	53/188 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		14/49 (29%)
		Homeobox	175..229	CDD:395001	25/53 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810