DRSC/TRiP Functional Genomics Resources

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Protein Alignment cad and lbl

DIOPT Version :10

Sequence 1:NP_001260641.1 Gene:cad / 35341 FlyBaseID:FBgn0000251 Length:445 Species:Drosophila melanogaster
Sequence 2:NP_001262805.1 Gene:lbl / 42541 FlyBaseID:FBgn0008651 Length:410 Species:Drosophila melanogaster


Alignment Length:403 Identity:84/403 - (20%)
Similarity:117/403 - (29%) Gaps:149/403 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   123 SGSSSSGGAPGAPQLNETN-------------------------SSIGVGGAGGGGGVGGATDGG 162
            :.|..|.|:|..|.|...|                         .|..:....|.|......:..
  Fly     9 ANSDVSVGSPSPPPLRSLNMKRLRLLRSPISLEHDRQKSSPVRVKSFSIADILGRGHEEDRVEKK 73

  Fly   163 PGS-APPNHQQHIAEGLPSP----------PITVSGSEISSPGAPTSAS-----SP--------- 202
            |.. |.||    ...|:|:|          |:.        |..|..|:     ||         
  Fly    74 PERIAIPN----ALPGVPAPLALINERLQIPLV--------PNCPPPAALHTFLSPALLHSYEQR 126

  Fly   203 -----HHHLAHHLSA--------------VANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPS 248
                 ...|..|..|              :|:.:.::..:..|.|   :|.:....|........
  Fly   127 LAWDYQRQLQEHFQAQAQLLRQMTLNPAIIASEDGSSERSQRSSS---SNGSTECCSPTQAEKVE 188

  Fly   249 KPPYFDWMKKPAYPAQPQP-DLSSSPNLEDLSDLLDASGK---------------TRT----KDK 293
            |....|.|:.|....:.|| ..|.|.....|..|...|.|               ||:    |.|
  Fly   189 KRSQEDRMEVPKKSPEEQPKGASKSSGDTPLDALFQLSTKNFDEEQDPATLNIFATRSNPKKKRK 253

  Fly   294 YRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNV 358
            .|..:|:.|..||||.:...:|::...:.|:|..|.||..||..||||||||             
  Fly   254 SRTAFTNQQIFELEKRFLYQKYLSPADRDEIAGGLGLSNAQVITWFQNRRAK------------- 305

  Fly   359 MGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHPHLAAHSHSLAAVAAHS 423
                                     |...:......:....||.....|:.:.|:|      .|.
  Fly   306 -------------------------LKRDMEELKKDVQCEKIPDQSADPNRSHHNH------PHY 339

  Fly   424 HQLQQQHSAQMSA 436
            || |.||.|.|.:
  Fly   340 HQ-QHQHYAHMQS 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cadNP_001260641.1 Homeodomain 293..348 CDD:459649 24/54 (44%)
lblNP_001262805.1 COG5576 206..332 CDD:227863 39/163 (24%)
Homeodomain 252..308 CDD:459649 25/93 (27%)

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