Protein Alignment cad and msx2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: XP_002936749.1
• Gene: msx2 / 394987
• XenbaseID: XB-GENE-852974
• Length: 256
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 71/339 - (20%)
• Similarity: 110/339 - (32%)
• Gaps: 150/339 - (44%)

  Fly    81 GEWHSPASSTADNF---VQNVPTSAHQLM-------QQHHHHHAHASSSSASSGSSSSG--GAPG 133
            |:.| |..|.:|:.   |.::|.|...||       :..|.....||::.::......|  .:|.
 Frog    17 GQVH-PTLSPSDDHKIKVSSLPFSVEALMADKRVPKEAPHLRGVDASAAGSTPRHLHMGIRDSPS 80

  Fly   134 APQLNETNSSIGVGGAGGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTS 198
            .|.|.:|..:..|.......|...:.|||..|.||.|.
 Frog    81 PPGLTKTFETSSVKSENSEDGTTWSKDGGSYSPPPRHL--------------------------- 118

  Fly   199 ASSPHHHLAHHLSAVANNNNNNNNNNNSPST-----HNNNNNNNSVSNNNRTSPSKPPYFDWMKK 258
                                       ||||     |..|                       :|
 Frog   119 ---------------------------SPSTCTLRKHKTN-----------------------RK 133

  Fly   259 PAYPAQPQPDLSSSPNLEDLSDLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSE 323
            |..|                                   :|..|.|.||:::...:|::|..::|
 Frog   134 PRTP-----------------------------------FTTSQLLALERKFRQKQYLSIAERAE 163

  Fly   324 LAQTLSLSERQVKIWFQNRRAKERKQNKKGSDPNVMGVGVQHADYSQL-LDAKAKLEPGLHLSHS 387
            .:.:|:|:|.||||||||||||.::              :|.|:..:| :.||..|.||.    |
 Frog   164 FSSSLNLTETQVKIWFQNRRAKAKR--------------LQEAEIEKLKMAAKPILPPGF----S 210

  Fly   388 LAHSMN-PMAAMNI 400
            :...:| |:.|.::
 Frog   211 IPFPINSPIQAASL 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)
msx2	XP_002936749.1	Homeodomain	132..188	CDD:459649	26/90 (29%)