Protein Alignment cad and Dbx

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_647677.2
• Gene: Dbx / 38254
• FlyBaseID: FBgn0261723
• Length: 741
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 128/596 - (21%)
• Similarity: 183/596 - (30%)
• Gaps: 246/596 - (41%)

  Fly     3 SHYYNTLPYTQKHSAANLAYASAAGQPWNWTPNYHHTPP----NHQFLGDVDSSHAAHHAAAAHQ 63
            ||.|      |:|......::....||.. .|.:.|:.|    :|........:|..|.|...||
  Fly   193 SHQY------QQHHQQQQPHSHPQHQPLA-VPGHQHSHPHSHHHHHHHPGAGHAHFPHPAFLTHQ 250

  Fly    64 MYYNSHHM----------FHSAAAASAGEWHSPASSTADNFVQNVPTSAHQLMQQHHHHHAHASS 118
            :..:.||.          .:|....:|....||.|:.:|:                .::|..:::
  Fly   251 LPPHQHHQQQQHVQQQHPGNSCQPQTASSSSSPGSTISDS----------------DNNHGASTA 299

  Fly   119 SSASSGSSSSGGAPGAPQLNETNSS-------------------IGVGGAGGGGGVGGATDGGPG 164
            :...||:.:||......:|..:|..                   :|.||.||||| ||...|.|.
  Fly   300 NGNGSGTGNSGQDARPHELANSNPDEDSSASRRLTQDKQQQQQLLGAGGTGGGGG-GGHGHGHPT 363

  Fly   165 SAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHH--LAHHLSAVANNNNNNNNNNNSP 227
            ..||.....||:.:||.|         :|..|.:.:.||.|  |||
  Fly   364 PPPPPPPPVIAKPMPSRP---------TPFLPHTLNHPHLHSLLAH------------------- 400

  Fly   228 STHNNNNNNNSVSNNNRTSPSKPPYFDWMKK--PAYPAQPQPDLSSSPNLEDLSDLLDASGKTRT 290
                                .:.||.....:  |..|.|..|...|:            .||.|.
  Fly   401 --------------------CRNPYMSVGAQVFPLPPGQGFPWAHST------------RGKPRR 433

  Fly   291 KDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRR-----AKERK-- 348
            ....|.|::|.||..|||.:...:||:...:.:||:.|.|.:.||||||||||     :|||:
  Fly   434 GMMRRAVFSDSQRKGLEKRFQQQKYISKPDRKKLAERLGLKDSQVKIWFQNRRMKWRNSKERELL 498

  Fly   349 ----------QNKKGSDPNV--------------------------------------------- 358
                      .||...:|::
  Fly   499 ASGGSRDQTLPNKNNPNPDLSDAKCDRPLTPLSPSLLSPNGSATPPPPGAVAKDEPPTAAVTPKS 563

  Fly   359 -----------MGVGVQHADYSQLL----------------------DAKAKLEPGLHLSHSLAH 390
                       :|.|:|.:....||                      .:.|...||:..|...|.
  Fly   564 PQSVSSRSSPSVGYGLQISSPPPLLTSLKMGDQSASATPTPLPGTTVSSAAASPPGVTASEFQAK 628

  Fly   391 SMNPMAAMNIPA----------------------MRLH--PHLAA-HSHSLAAVAA-----HSHQ 425
            ....|....:.|                      .:||  ||.:| ....|||.||     |.||
  Fly   629 INAEMQKQLVAADLKFKLENSIQEAKQRRFEQLQQQLHHSPHFSAMREVELAAAAAAAQLHHHHQ 693

  Fly   426 LQQQHSAQMSA 436
            .|||...|..|
  Fly   694 QQQQQQQQQHA 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	26/59 (44%)
Dbx	NP_647677.2	Homeodomain	437..491	CDD:459649	24/53 (45%)