DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cad and vax1

DIOPT Version :9

Sequence 1:	NP_001260641.1	Gene:	cad / 35341	FlyBaseID:	FBgn0000251	Length:	445	Species:	Drosophila melanogaster
Sequence 2:	NP_919391.2	Gene:	vax1 / 373870	ZFINID:	ZDB-GENE-030904-9	Length:	317	Species:	Danio rerio

Alignment Length:	145	Identity:	47/145 - (32%)
Similarity:	77/145 - (53%)	Gaps:	14/145 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   282 LDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKE 346
            ||...:|||......:|    |||:|.:.|  :|:..|.::|||:.|:|||.|||:||||||.|:
Zfish    89 LDRPKRTRTSFTAEQLY----RLEMEFQRC--QYVVGRERTELARQLNLSETQVKVWFQNRRTKQ 147

  Fly   347 RKQNKKGSD-PNVMGVGVQHADYSQLLDAKAKLE----PGLHLSHSLAHSMNPMAAMNIPAMRLH 406
            :|...|.|: .:|:..........:||:....|.    ||| |.|..:.|:.  :|:..|::.:.
Zfish   148 KKDQGKDSELRSVVSETAATCSVLRLLEQGRLLTPPGLPGL-LPHCGSSSLG--SALRGPSLGIT 209

  Fly   407 PHLAAHSHSLAAVAA 421
            .:..:.|.|.::..:
Zfish   210 ANGGSSSSSSSSAGS 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeobox	295..347	CDD:278475	25/51 (49%)
vax1	NP_919391.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..62
		Homeobox	95..148	CDD:278475	28/58 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	203..248		3/22 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810