Protein Alignment cad and Gsx2

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001131035.2
• Gene: Gsx2 / 364140
• RGDID: 1308047
• Length: 305
• Species: Rattus norvegicus
• Alignment Length: 289
• Identity: 78/289 - (26%)
• Similarity: 107/289 - (37%)
• Gaps: 97/289 - (33%)

  Fly   113 HAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGAGGGGGVGGATDG----------GPGS-- 165
            |.|:|...|.:|    |||.|.           .|.|..||||.|.|..          |||.
  Rat    68 HLHSSRPPAGAG----GGATGT-----------AGAAVAGGGVAGGTGALPLLKSQFSPGPGDAQ 117

  Fly   166 -------------APPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVANNN 217
                         ||.:|..|.....|......:.:..::..|..:...|.||     :.|.
  Rat   118 FCPRVSHAHHHHHAPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAAALGHPQHH-----APVC--- 174

  Fly   218 NNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLL 282
                    :.:|:|               .|.|..|..:      .....|.|..||
  Rat   175 --------AATTYN---------------VSDPRRFHCL------TMGGSDTSQVPN-------- 202

  Fly   283 DASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKER 347
               ||     :.|..:|..|.||||:|:.::.|::..|:.|:|..|:|||:||||||||||.|.:
  Rat   203 ---GK-----RMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHK 259

  Fly   348 KQNKKGSDPNVMG---VGVQHADYSQLLD 373
            |:.|..|..|...   ||.| |.|::..|
  Rat   260 KEGKGASRNNHASCKCVGSQ-AHYARSED 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	27/54 (50%)
Gsx2	NP_001131035.2	Homeodomain	204..260	CDD:459649	28/60 (47%)