Protein Alignment cad and pnx

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_840087.1
• Gene: pnx / 352939
• ZFINID: ZDB-GENE-030328-42
• Length: 182
• Species: Danio rerio
• Alignment Length: 208
• Identity: 56/208 - (26%)
• Similarity: 78/208 - (37%)
• Gaps: 70/208 - (33%)

  Fly   227 PSTHNNNNNNNSVSNNNR----TSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASGK 287
            |:..|.......:|||..    |||::.|                   |:||:.:.|     :.|
Zfish    24 PAKFNGTRETREISNNRESPKTTSPTQEP-------------------SAPNIANAS-----AAK 64

  Fly   288 TRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            .::| :.|..:|..|...||:.:.:|.|:::..:..:|..|.|||.||||||||||.|.:|:
Zfish    65 VKSK-RIRTAFTLDQLRILERSFQSSHYLSVFERHCIASALGLSETQVKIWFQNRRTKWKKE--- 125

  Fly   353 GSDPNVMGVGVQHADYSQLLDAKAKLEPGLHLSHSLAHSMNPMAAMNIPAMRLHP-HLAAHSHSL 416
                               ||...    |...||..     |.|....|.|...| |.|.|
Zfish   126 -------------------LDGHG----GEEQSHCA-----PTALTQNPIMYALPGHHANH---- 158

  Fly   417 AAVAAHSHQLQQQ 429
                 |.|...||
Zfish   159 -----HVHYYPQQ 166

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	23/54 (43%)
pnx	NP_840087.1	Important for interaction with tle3a. /evidence=ECO:0000269|PubMed:12642490	1..34		2/9 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		13/62 (21%)
		Homeodomain	68..124	CDD:459649	24/56 (43%)