Protein Alignment cad and HOXD9

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_055028.3
• Gene: HOXD9 / 3235
• HGNCID: 5140
• Length: 352
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 87/312 - (27%)
• Similarity: 126/312 - (40%)
• Gaps: 58/312 - (18%)

  Fly    77 AASAGEWHS----PASSTADNFVQNVPTSAHQLMQQHHHHHAHASSSSASSGSSSSG-------- 129
            ||:|.|:.|    |.|:........||:...........:|.:......::.:|..|
Human    57 AATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPYVPPPPLAASASEPGRYVRSWME 121

  Fly   130 GAPGAPQLNETNSSIGVGGAGGGGGVGGATDGGPGSAP------PNHQQHIA---EGLPSPPITV 185
            ..||.|           ||||||||.||   ||||..|      |.:.:|..   |...:|....
Human   122 PLPGFP-----------GGAGGGGGGGG---GGPGRGPSPGPSGPANGRHYGIKPETRAAPAPAT 172

  Fly   186 SGSEISSPGAPTSASSPHHHLAHHLSAVANNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSP--- 247
            :.|..||.....|:||....     .:||..:..::....|   .|:.....:.:....|.|
Human   173 AASTTSSSSTSLSSSSKRTE-----CSVARESQGSSGPEFS---CNSFLQEKAAAATGGTGPGAG 229

  Fly   248 ----------SKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLSDLLDASG--KTRTKDKYRVVYTD 300
                      |:|........|....:.:....|.|..:.|.....|:.  ..|:..|.|..||.
Human   230 IGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANWIHARSTRKKRCPYTK 294

  Fly   301 FQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRAKERKQNKK 352
            :|.||||||:..:.|:|..|:.|:|:.|:|:||||||||||||.|.:|.:|:
Human   295 YQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMKMKKMSKE 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	31/54 (57%)
HOXD9	NP_055028.3	Hox9_act	11..>164	CDD:461369	32/120 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	126..208		28/100 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	229..276		6/46 (13%)
		Homeodomain	286..337	CDD:459649	28/50 (56%)