Protein Alignment cad and HOXB7

DIOPT Version :10

• Sequence 1: NP_001260641.1
• Gene: cad / 35341
• FlyBaseID: FBgn0000251
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_004493.3
• Gene: HOXB7 / 3217
• HGNCID: 5118
• Length: 217
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 74/276 - (26%)
• Similarity: 99/276 - (35%)
• Gaps: 86/276 - (31%)

  Fly    86 PASSTADNFVQNV-PTSAHQLMQQHHHHHAHASSSSASSGSSSSGGAPGAPQLNETNSSIGVGGA 149
            ||||:.  |.... |.........:.....:.:.|.||..:|..|..||             ||.
Human    15 PASSSV--FATGAFPEQTSCAFASNPQRPGYGAGSGASFAASMQGLYPG-------------GGG 64

  Fly   150 GGGGGVGGATDGGPGSAPPNHQQHIAEGLPSPPITVSGSEISSPGAPTSASSPHHHLAHHLSAVA 214
            ..|....|....|.|..|.:...|.|      |...:.|.: .||....|:.........|:|
Human    65 MAGQSAAGVYAAGYGLEPSSFNMHCA------PFEQNLSGV-CPGDSAKAAGAKEQRDSDLAA-- 120

  Fly   215 NNNNNNNNNNNSPSTHNNNNNNNSVSNNNRTSPSKPPYFDWMKKPAYPAQPQPDLSSSPNLEDLS 279
                                     .:|.|..|       ||:
Human   121 -------------------------ESNFRIYP-------WMR---------------------- 131

  Fly   280 DLLDASGKTRTKDKYRVVYTDFQRLELEKEYCTSRYITIRRKSELAQTLSLSERQVKIWFQNRRA 344
                :||..|.:.  |..||.:|.||||||:..:||:|.||:.|:|.||.|:|||:||||||||.
Human   132 ----SSGTDRKRG--RQTYTRYQTLELEKEFHYNRYLTRRRRIEIAHTLCLTERQIKIWFQNRRM 190

  Fly   345 KERKQNKKGSDPNVMG 360
            |.:|:||. :.|...|
Human   191 KWKKENKT-AGPGTTG 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cad	NP_001260641.1	Homeodomain	293..348	CDD:459649	32/54 (59%)
HOXB7	NP_004493.3	Antp-type hexapeptide	126..131		2/11 (18%)
		Homeodomain	138..194	CDD:459649	32/57 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..217		5/13 (38%)